whole-body physiology Archives | ��ϳԹ��Դ

President’s message: Progress and opportunity for science and medicine

Communications Department — Tue, 09 Jun 2026 16:00:32 +0000

his is an extraordinary moment in time for the biomedical sciences. Seven decades ago, the discovery of the structure of DNA sparked a revolution in understanding life. In the decades since, the knowledge of fundamental biology we have accumulated has led to innovative treatments for many difficult-to-treat diseases, and many more are now within reach....

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Fish oil may increase CTE risk after brain injury

Nick Wurm — Tue, 07 Apr 2026 11:30:07 +0000

Neurodegenerative conditions like chronic traumatic encephalopathy (CTE) are often called a silent pandemic. Even so-called “mild” concussions, like those sustained in contact sports, may have a cascading effect over time. CTE symptoms such as mood swings, memory loss, and depression may not appear for decades. A new study suggests one common dietary supplement may, in...

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Immune response to cancer may cause brain disease

Samuel Diamond — Wed, 25 Mar 2026 16:00:01 +0000

Consider two seemingly unrelated medical puzzles. First: Every day, our bodies produce hundreds of billions of new cells, many of which are mutated. If cancer arises from cellular mutation, why don’t we all have the disease all the time? Second: Severe autoimmune conditions like lupus and multiple sclerosis often strike without warning. No one knows...

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Let’s get on pancreatic cancer’s nerves

Margaret Osborne — Mon, 09 Feb 2026 13:54:57 +0000

Pancreatic cancer has a lot of nerve. Notoriously tricky to detect, the disease also often resists traditional therapy. So, researchers are urgently looking for new ways to disrupt tumor formation. Though scientists know that the nervous system can help cancer spread, its role in the disease’s earliest stages remains unclear. “One phenomenon that is known...

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Borniger wins Mark Foundation Emerging Leader Award

Gina Dipietro — Tue, 13 Jan 2026 17:00:17 +0000

��ϳԹ��Դ (CSHL) Associate Professor Jeremy Borniger is among five scientists to receive this year’s Bakewell Emerging Leader Award from The Mark Foundation for Cancer Research. The Award provides Borniger’s lab $750,000 over three years. Borniger’s research explores the potential of synthetic torpor—a hibernation-like metabolic state—as a novel anti-cancer strategy. By suppressing metabolism,...

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Day & night: Cancer disrupts the brain’s natural rhythm

Nick Wurm — Mon, 15 Dec 2025 16:00:32 +0000

“The brain is an exquisite sensor of what’s going on in your body,” says ��ϳԹ��Դ Assistant Professor Jeremy Borniger. “But it requires balance. Neurons need to be active or inactive at the right times. If that rhythm goes out of sync even a little bit, it can change the function of the...

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Borniger reaches Cancer Grand Challenges finals

Samuel Diamond — Wed, 24 Sep 2025 09:00:41 +0000

��ϳԹ��Դ (CSHL) Assistant Professor Jeremy Borniger has been selected for the final stages of a Cancer Grand Challenges research initiative as part of team NEUROIMPACT. The team seeks to determine how the nervous system senses and responds to cancers. In identifying the nervous system’s role in tumor growth and cancer metastasis, they...

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Go inside cancer’s biology

Nick Wurm — Mon, 22 Sep 2025 16:00:16 +0000

What happens inside and around a cancer cell? How does a tumor’s interaction with its surroundings contribute to cancer’s growth and spread? These questions could lead to a new generation of cancer therapies with fewer harmful side effects. Appropriately, they’re being asked and answered by a new generation of scientists at forums like the Cold...

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Patient insights inspire discovery

Samuel Diamond — Wed, 03 Sep 2025 15:00:17 +0000

“My body is all used up, and I have no will left to live.” Those are the first words of a new essay written by ��ϳԹ��Դ Associate Professor Tobias Janowitz. They’re the words of his late mother during the final days of her life. “A perceptive woman who survived a childhood shaped...

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Ever use cortisone? Thank one farmer and two CSHL scientists

Jen A. Miller — Wed, 20 Aug 2025 13:00:16 +0000

Addison’s disease is no walk in the park. The disorder occurs when a person’s adrenal glands don’t make enough cortisol. This hormone plays a key role in multiple bodily functions, including metabolism and immune response. People with Addison’s disease can feel fatigued or nauseous, suffer from chronic pain, and lose unhealthy amounts of weight. If...

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Mind-blowing neuroscience research

Communications Department — Tue, 22 Jul 2025 11:30:19 +0000

The brain is the most complex and powerful part of the human body. When things are working as they should, we don’t notice at all. However, any number of conditions can disrupt healthy brain function. ��ϳԹ��Դ (CSHL) neuroscientists focus on understanding how neural connections in the brain translate into behavior. Their research...

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A new body of knowledge

Communications Department — Tue, 24 Jun 2025 11:30:00 +0000

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Exposomics: Holistic health without the snake oil

Samuel Diamond — Thu, 12 Jun 2025 11:30:27 +0000

We live in the age of -omics. We have genomics to study complete sets of DNA. We have proteomics focused on all the proteins within our cells. And we have metabolomics for metabolites like sugars and lipids. Despite their massive reach and intense focus, these fields have blind spots. They’re both in the margins and...

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At the Lab: An evening out with the brain and body

Communications Department — Tue, 10 Jun 2025 11:30:28 +0000

Typically, if you hear someone in a bar talking about “conversations” between the brain and the body, you might want to call them a cab. Not this time! Barstool philosophy meets brain-body physiology in our latest At the Lab podcast, featuring audio from CSHL Assistant Professor Jeremy Borniger’s recent Cocktails & Chromosomes talk.

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At the Lab: UTIs in women’s health

Communications Department — Tue, 13 May 2025 11:30:13 +0000

“It started with an accident observation,” says CSHL Associate Professor Camila dos Santos. That observation? A group of lab mice with urinary tract infections also had breast abnormalities. What might this mean for women’s health? And how does such an accident even happen to begin with? Tune in and find out.

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It’s not you—it’s cancer

Jennifer Michalowski — Thu, 10 Apr 2025 18:00:51 +0000

AI generated voice with Tobias Janowitz’s actual voice Cancer ravages both body and mind. If you’ve ever lost loved ones to the disease, you might recognize the physical and emotional changes cancer patients often endure during their final months. They seem drained of strength and spirit. Even people who’ve maintained a positive outlook throughout their...

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CSHL holds first-ever cancer neuroscience course

Nick Wurm — Mon, 24 Mar 2025 11:30:47 +0000

The brain controls the body, in large part, through nerves. So, what happens when nerves form new connections with tumors? How does the nervous system drive cancer progression? How do these interactions influence anti-cancer therapies? A burgeoning new field known as cancer neuroscience aims to answer these questions. But how? How does one solve a...

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Janowitz elected to ASCI

Samuel Diamond — Mon, 27 Jan 2025 12:30:34 +0000

��ϳԹ��Դ Associate Professor Tobias Janowitz has been elected to the American Society for Clinical Investigation (ASCI). Janowitz is recognized for his outstanding scholarly research, which approaches cancer from a whole-body perspective. He has led clinical trials and published authoritative studies on cancer cachexia, a debilitating condition that affects patients in the late...

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A comeback story at Genes & Development

Samuel Diamond — Thu, 23 Jan 2025 12:30:04 +0000

We regret to inform you that your manuscript has not been selected for publication. That’s how Andrew Dillin’s relationship with Genes & Development (G&D) begins. The scientific journal, published by ��ϳԹ��Դ (CSHL) Press, fields hundreds of article submissions each year. It’s considered one of the top publications in all of developmental and...

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CSHL and Range ETFs launch new partnership

Lisa Cruz — Thu, 21 Nov 2024 12:30:49 +0000

More than two million new cases of cancer will be diagnosed in the United States in 2024, according to the National Cancer Institute. Range Cancer Therapeutics ETF (Nasdaq: CNCR) is partnering with ��ϳԹ��Դ (CSHL) to highlight CSHL’s pioneering role in advancing cancer research. Through the partnership, 23% of revenues generated by fees...

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whole-body physiology Archives | ���ϳԹ���Դ