click chemistry Archives | ��ϳԹ��Դ

A secret weapon against superbugs

Gina Dipietro — Tue, 21 Jul 2026 16:00:11 +0000

Staphylococcus aureus (MRSA) bacteria, shown here. The bacteria cause staph infections, which can spread rapidly in hospitals and nursing homes, often with deadly results. Image: © Maxim - stock.adobe.com" data-description="Colorful microscope image showing orange, yellow, and white spheres among pink and yellow fibrous strands." />Antibiotic resistance has quietly become one of the greatest threats to global healthcare. Each year, drug-resistant bacteria claim lives by rendering once-reliable antibiotics ineffective, turning routine surgeries, cancer treatments, and even common infections into potentially life-threatening events. Scientists around the world are racing to find new ways to stay ahead of these evolving pathogens. The...

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NCI grants support ‘natural’ cancer research

Margaret Osborne — Mon, 11 Aug 2025 11:30:42 +0000

Complex chemical and biological processes are fundamental for all life on Earth and all the organs inside us. When something goes wrong with these processes, diseases like cancer can arise. At the ��ϳԹ��Դ (CSHL) Cancer Center, Professor John Moses and colleagues use click chemistry, a fast and reliable technique for linking molecules,...

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Moses elected Fellow of Learned Society of Wales

Samuel Diamond — Tue, 29 Apr 2025 08:00:53 +0000

��ϳԹ��Դ (CSHL) Professor John Moses has been named a Fellow of the Learned Society of Wales. He is one of 56 leaders and experts elected to this prestigious role from academia, health services, and the public sphere. At CSHL, Moses uses a revolutionary process called click chemistry to identify and test potential...

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Deciphering brain diseases with click chemistry

Communications Department — Tue, 18 Feb 2025 12:30:53 +0000

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At the Lab Episode 13: A more sustainable chemistry

Communications Department — Tue, 02 Jul 2024 11:30:33 +0000

Some of the world’s most precious chemicals are biological in nature. But what can we do when nature offers only a limited supply? This week’s podcast starts on the other side of the globe and ends up back here At the Lab with CSHL’s resident click chemist, Professor John Moses.

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Wrexham University awards John Moses Honorary Fellowship

Luis Sandoval — Thu, 13 Jun 2024 11:30:25 +0000

They say you can’t go home again. Try telling that to ��ϳԹ��Դ (CSHL) Professor John Moses. The chemist recently returned to his hometown of Wrexham, a city in the northeast corner of Wales, near the country’s border with England. There, he received a hero’s welcome as he was awarded an Honorary Fellowship...

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Nobel laureate honored at CSHL chemistry symposium

Luis Sandoval — Mon, 15 Apr 2024 11:30:48 +0000

Pharmaceutical companies need to make drugs quickly. They need to produce chemical compounds in large amounts. And they need these compounds to have as few harmful side effects as possible. But in reality, many chemical reactions are imperfect and inefficient. Click chemistry is a revolutionary process that allows scientists to cleanly and quickly uncover more...

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Click, click, boom—150 new molecules

Jennifer Michalowski — Thu, 04 Apr 2024 11:30:05 +0000

Chemical Science, the Royal Society of Chemistry’s flagship journal, calls accelerated SuFEx click chemistry “a robust platform for drug discovery.” Image: © alex_aldo - stock.adobe.com" data-description="" />��ϳԹ��Դ (CSHL) chemists have created a new collection of molecular compounds and begun testing them as potential leads in the search for new drugs. Among these molecules, they found several that show promise for development as antibiotics and cancer therapies. Sounds like a eureka moment? Well, sort of. But it’s more a...

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Cocktails & Chromosomes: Molecules to change the world

Communications Department — Thu, 14 Mar 2024 11:30:57 +0000

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CSHL makes a splash with Swim Across America

Communications Department — Mon, 21 Aug 2023 11:30:26 +0000

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CSHL harnesses biology’s favorite chemical

Jennifer Michalowski — Wed, 07 Jun 2023 15:00:04 +0000

For chemists like ��ϳԹ��Դ (CSHL) Professor John Moses, diversity is a gateway to discovery. The more molecules scientists have to explore, the more likely it is they will find something useful. With the latest advancement from Moses’ lab, they can now quickly assemble a vast array of complex molecules. Among those molecules,...

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New shape-shifting antibiotics could fight deadly infections

Margaret Osborne — Tue, 04 Apr 2023 11:30:40 +0000

Staphylococcus aureus (MRSA). MRSA is a superbug resistant to several kinds of antibiotics. According to one estimate, it killed more than 100,000 people worldwide in 2019. Image: © Kateryna_Kon – stock.adobe.com" data-description="" />In the United States alone, drug-resistant bacteria and fungi infect almost 3 million people per year and kill about 35,000. Antibiotics are essential and effective, but in recent years overuse has led to some bacteria developing resistance to them. The infections are so difficult to treat, the World Health Organization deemed antibiotic resistance a top...

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A new, sustainable source for a promising cancer killer

Luis Sandoval — Thu, 23 Mar 2023 16:00:04 +0000

Tabernaemontana corymbosa, seen above, produces a natural cancer-killing molecule. Normally, you’d have to travel all the way to Malaysia to find it. Instead, CSHL chemists have recreated this cancer killer in the lab using sustainable chemistry techniques." data-description="" />Plants produce all types of curious chemicals. Some deter predators. Some smell wonderful. Some even have medicinal value. One of these hidden gems is (–)-jerantinine A (JA), a molecule with remarkable anticancer properties, produced by a plant called Tabernaemontana corymbosa. Unfortunately, access to this Malaysian jungle plant and its promising chemical compound has been limited....

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CSHL in pursuit of shape-shifting antibiotics

Eliene Augenbraun — Mon, 25 Apr 2022 16:00:14 +0000

��ϳԹ��Դ (CSHL) Professor John E. Moses and Research Investigator Joshua Homer were awarded more than $325,000 by New York State to develop a new type of antibiotic that can treat bacteria that have become drug-resistant. New York Governor Kathy Hochul announced the award and over $15 million worth of research awards as...

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Tools of the trade at CSHL: Robotic microwave

Communications Department — Thu, 24 Feb 2022 12:30:41 +0000

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Teaching an old chemical new tricks

Luis Sandoval — Mon, 06 Dec 2021 14:00:09 +0000

They say you can’t teach an old dog new tricks, but can you do new tricks with old chemical catalysts? ��ϳԹ��Դ Professor John E. Moses and his team have paired a catalyst called “Barton’s base” developed in the 1980s with a new family of chemical reactions. This powerful combination results in a...

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Unstoppable chemistry

Luis Sandoval — Fri, 05 Nov 2021 11:30:30 +0000

ow do you take the guesswork out of chemistry? John E. Moses, ��ϳԹ��Դ’s first professor of chemistry, likes things that are fast and reliable. He is especially fond of rapid chemical reactions, and he’s not the only one. Drug companies need to make drugs quickly, in large amounts, and with few toxic...

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The “click” in click chemistry

Luis Sandoval — Thu, 04 Nov 2021 11:30:21 +0000

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Tools of the trade at CSHL: NMR

Luis Sandoval — Fri, 29 Oct 2021 20:00:39 +0000

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F.M. Kirby Foundation donates $115K for chemistry research

Luis Sandoval — Tue, 12 Oct 2021 11:30:43 +0000

On September 16th, 2021 the F.M. Kirby Foundation donated $115,000 to support chemistry research at ��ϳԹ��Դ (CSHL) Professor John E. Moses’ laboratory. Moses is a leader in click chemistry and how to synthesize new molecules useful for drugs, biological tools, and material science. Click chemistry uses a unique type of reaction that...

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