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Nobel laureate honored at CSHL chemistry symposium

image of Bruce Stillman, John Prufeta, David Tuveson, John Moses, and Barry Sharpless
Left to right: CSHL President & CEO Bruce Stillman, Medical Excellence Capital General Partner & CEO John Prufeta, CSHL Professor and Cancer Center Director David Tuveson, CSHL Professor John E. Moses, and two-time Nobel laureate K. Barry Sharpless

Pharmaceutical companies need to make drugs quickly. They need to produce chemical compounds in large amounts. And they need these compounds to have as few harmful side effects as possible. But in reality, many chemical reactions are imperfect and inefficient. Click chemistry is a revolutionary process that allows scientists to cleanly and quickly uncover more sustainable sources for potential new drugs and other synthetic materials. The term comes from chemicals 鈥渃licking鈥 together like LEGO bricks. It was coined by K. Barry Sharpless, a pioneer in the field.

Sharpless isn鈥檛 just a two-time Nobel laureate. He was also a mentor to two 黑料吃瓜资源 (CSHL) scientists, Cancer Center Director David Tuveson and Professor John Moses. On March 2, CSHL hosted a symposium celebrating the work of Sharpless and exploring 鈥淭he Future of Click Chemistry.鈥 The event featured the field鈥檚 top minds from the U.S., Canada, Europe, and Asia, including Sharpless and Moses. Researchers presented their latest advances, pointing to many exciting new directions for the field. Event sponsor (MEC) announced a $100,000 donation to support click chemistry research in CSHL鈥檚 Moses and Tuveson labs. Meanwhile, Sharpless stood approvingly alongside his former apprentices.

CSHL Professor John E. Moses and collaborator two-time Nobel laureate K. Barry Sharpless demonstrate click chemistry in action, synthesizing a helical polymer in a matter of minutes.

From Moses鈥 perspective, the 鈥渇uture of click chemistry鈥 is largely owed to his mentor’s groundbreaking work. Sharpless鈥 achievements, he said, 鈥渙pened the doors to revolutionary advances in science, medicine, and drug discovery. His legacy is a testament to the power of simplicity and precision in science, promising new horizons in healthcare.鈥

It鈥檚 a legacy that Professors Tuveson and Moses are excited to uphold and build upon for many years to come.

Written by: Luis Sandoval, Communications Specialist | [email protected] | 516-367-6826

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