Adam Siepel Archives | ��ϳԹ��Դ

At the Lab Season 1 Research Rewind: AI+

Communications Department — Tue, 29 Oct 2024 11:30:55 +0000

How do we interpret what AI tells us without knowing the logic of its own interpretations? How do we make artificial intelligence more efficient and reliable without fully understanding biological intelligence’s efficiency and reliability problems? This season’s final Research Rewind brings us from the realm of quantitative biology to neuroscience, genomics, and beyond. You’ll hear...

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How does cancer spread? Follow the map

Jen A. Miller — Wed, 25 Sep 2024 11:30:07 +0000

Metastatic cancer can be a devastating diagnosis. The cancer is spreading. It may travel to multiple organs in the body. This could mean more pain and ultimately, death. Unfortunately, just how cancer spreads remains unclear. But now, ��ϳԹ��Դ (CSHL) Professor Adam Siepel and colleagues have a way to better understand that process....

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At the Lab Episode 8: Birds of a feather

Communications Department — Tue, 21 May 2024 11:30:19 +0000

Cappuccino anyone? This week At the Lab, CSHL Professor Adam Siepel introduces the capuchino seedeater—a South American subspecies known for its ultraviolet plumage. Join us on a voyage across evolution’s “islands of differentiation” to find out how these birds got their distinct colors.

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The CSHL School of Biological Sciences’ class of 2024

Communications Department — Sun, 05 May 2024 22:00:34 +0000

The ��ϳԹ��Դ (CSHL) School of Biological Sciences (SBS) takes an innovative approach to advanced science education. Graduates of the doctoral program go on to pursue diverse careers. This year, the SBS awarded 11 Ph.D. degrees. Here, members of the class of 2024 reflect on their time and experiences at CSHL. Salomé Carcy...

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A quiz for the ages

Communications Department — Mon, 29 Jan 2024 12:30:33 +0000

{“questions”:{“4ib35”:{“id”:”4ib35″,”mediaType”:”image”,”answerType”:”text”,”imageCredit”:””,”image”:”https:\/\/www.cshl.edu\/wp-content\/uploads\/2023\/11\/Pancreatic_tissue_with_CAR_T_cells.jpg”,”imageId”:”67343″,”video”:””,”imagePlaceholder”:””,”imagePlaceholderId”:””,”title”:”Modified T cells may hold the key to the mythical fountain of youth. CSHL scientists discovered just one dose is enough to rejuvenate older mice. What happened to these mice after T cell treatment?”,”desc”:”Assistant Professor Corina Amor Vegas discovered T cells can be reprogrammed to fight aging. After using them to eliminate specific cells in...

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Holy immunity! Bat genes key against COVID, cancer

Nick Wurm — Mon, 16 Oct 2023 11:30:39 +0000

Artibeus jamaicensis, the Jamaican fruit bat (seen here), and Pteronotus mesoamericanus, the Mesoamerican mustached bat." data-description="" />Bats have acquired remarkable traits throughout their evolution. They’re the only mammals that can fly, and they live much longer than other animals their size. But perhaps most impressive is their robust immune system. It protects bats from viruses that wreak havoc in humans, like COVID-19 or Ebola. It also keeps bats relatively cancer-free. How?...

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How evolved is your knowledge?

Nick Fiore — Thu, 26 Jan 2023 12:30:06 +0000

{“questions”:{“bg9to”:{“id”:”bg9to”,”mediaType”:”image”,”answerType”:”text”,”imageCredit”:”Image: \u00a9cooperr – stock.adobe.com”,”image”:”https:\/\/www.cshl.edu\/wp-content\/uploads\/2023\/01\/Book_open_pages.jpg”,”imageId”:”62993″,”video”:””,”imagePlaceholder”:””,”imagePlaceholderId”:””,”title”:”Described as a \u201cbook of life,\u201d what is the name of the monumental research effort that sequenced about 92% of all human DNA, bringing scientists closer to deciphering our evolutionary history?”,”desc”:”Completed in 2003 by an international consortium of research institutions, including CSHL, the Human Genome Project (HGP) laid the foundations for modern...

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Exposing the evolutionary weak spots of the human genome

Nick Wurm — Thu, 22 Sep 2022 11:30:38 +0000

Mutations can be good and bad. Sometimes they help an organism adapt and survive. Other times they are so harmful that an organism can’t survive or reproduce. ��ϳԹ��Դ (CSHL) Professor Adam Siepel’s team has created a computer program that tracks the history of harmful mutations in the human genome throughout evolution. They...

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CSHL Ph.D. program: Graduating class of 2021

Luis Sandoval — Sun, 22 Aug 2021 21:35:14 +0000

The ��ϳԹ��Դ (CSHL) School of Biological Sciences takes an innovative approach to advanced education. Graduates of the doctoral program pursue diverse careers. This year, seven students were awarded Ph.D. degrees. Here they recall memories and experiences that they take from the Laboratory. Benjamin Thomas Berube Saint Anselm College Elisabeth Sloan Livingston Fellow...

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Birds of a feather do flock together

Jennifer Michalowski — Tue, 17 Nov 2020 20:45:42 +0000

Sporophila hypoxantha. Illustration: Ben Wigler." data-description="" />Nearly 200 years ago, Charles Darwin noted striking diversity among the finches of the Galapagos Islands, and his observations helped him propose the role of natural selection in shaping species. Today, some biologists focus their attention on a related group of birds, the finch-like capuchino seedeaters of South America, and their studies are deepening our...

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Bridge to education

Communications Department — Sun, 15 Dec 2019 19:00:17 +0000

Recognized again this year as the world’s leading biology research institution, ��ϳԹ��Դ is relentless in leveraging the latest technologies and methodologies to advance our scientific and education programs. This ranking is consistent with our mission to excel in research and education for the benefit of society. In this magazine, you will see...

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Making sense of the genome…at last

Communications Department — Fri, 06 Dec 2019 21:50:01 +0000

A couple years ago, the pioneering geneticist Craig Venter went viral by failing to appear in a video clip. The presenter of a TED talk—a biologist named Riccardo Sabbatini—welcomed Venter onto the stage to explain the staggering amount of information in the human genetic code. As people began to applaud, five assistants emerged from the...

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The Lab partners with award-winning magazine

Communications Department — Fri, 06 Dec 2019 14:49:56 +0000

We were as excited as new-world explorers when we launched Nautilus in 2013. We knew science magazines before us were content to report on the latest novel research and leave it at that. But we were after something more. We wanted to introduce readers to scientists doing the most fascinating research in myriad fields around...

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Research profile: Adam Siepel

Brian Stallard — Tue, 12 Nov 2019 15:34:23 +0000

In the mid-1980s, a rural hamlet called West Valley in upstate New York had a 13-year-old guru named Adam Siepel. A surprising number of folks knew who he was, or at least as surprising as that can be in a tight-knit community of just over 500 people. Locals would seek him out to teach them,...

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How does natural selection affect the genome?

Communications Department — Tue, 18 Dec 2018 20:18:17 +0000

For the last few decades, biologists have been sifting through the human genome in search of those parts that are most important. CSHL Adam Siepel explain how natural selection and evolutionary history can tell them where to look. In a recent paper, he and his colleagues take this a step forward, using the same concept...

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How much are we learning? Natural selection is science’s best critic

Brian Stallard — Mon, 17 Dec 2018 21:00:12 +0000

Cold Spring Harbor, NY — In 2003, the Human Genome Project revealed to the world the three billion chemical units within human DNA. Since that time, scientists have designed many ways to organize and assess this overwhelmingly large amount of information. Now, scientists at ��ϳԹ��Դ (CSHL) have determined that evolution can help...

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A science writer’s quest to understand heredity

Andrea Alfano — Wed, 30 May 2018 15:00:45 +0000

t this very moment, there is more Neanderthal DNA on Earth than there was when Neanderthals were alive. Bits of their DNA, inherited tens of thousands of years ago, persist in many of our genomes today. This astounding legacy is one of many revelations that renowned science writer Carl Zimmer uses to burst open readers’...

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Evolving sets of gene regulators explain some of our differences from other primates

Peter Tarr — Mon, 29 Jan 2018 16:00:41 +0000

Cold Spring Harbor, NY — Today, biologists add an important discovery to a growing body of data explaining why we’re different from chimps and other primate relatives, despite the remarkable similarity of our genes. The new evidence has to do with the way genes are regulated. It’s the result of a comprehensive genome-wide computational analysis...

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Base Pairs Episode 13: A lesson in class

Communications Department — Fri, 15 Dec 2017 19:57:16 +0000

Base Pairs podcast - In this episode, we share three distinct stories about classification in the life sciences and how genetic information is changing how we define important categories.

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A lesson in class

Brian Stallard — Fri, 15 Dec 2017 17:03:49 +0000

Base Pairs podcast Base Pairs is a podcast about “the power of genetic information.” And there’s no better example of that power than how genome sequencing has changed our understanding of biology. In this episode, experts from three very different fields in the life sciences share stories from their own research that showcase this change....

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Adam Siepel Archives | ���ϳԹ���Դ