prostate cancer Archives | ��ϳԹ��Դ

The Unspoken Truth: A Dialogue on Prostate Cancer

Communications Department — Tue, 30 Jun 2026 16:00:01 +0000

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From lab discovery to patient care

Communications Department — Tue, 17 Feb 2026 12:30:27 +0000

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The journey: One lab’s long winding road to cancer discovery

Margaret Osborne — Wed, 15 Oct 2025 11:30:59 +0000

As many as one in eight men in America will be diagnosed with prostate cancer at some point in their lives. About one in 44 will die from it. “Prostate cancer is very common,” ��ϳԹ��Դ (CSHL) Professor Lloyd Trotman says. “The vast majority of prostate cancers remain slow-growing and will never be...

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Lessons learned in time: CSHL’s Symposium on aging

Communications Department — Wed, 11 Jun 2025 11:30:58 +0000

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From finance to restaurateur to men’s health advocate

Lisa Cruz — Thu, 24 Apr 2025 11:30:32 +0000

Self-described serial entrepreneur Tom Milana was not expecting a routine doctor’s appointment to turn into a mission to educate men about health and wellness. At just 48 years young, Milana was diagnosed with prostate cancer. That was 10 years ago. An early diagnosis and intervention meant Milana was cured, but the path was set for...

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At the Lab: A vitamin for prostate cancer

Communications Department — Tue, 08 Apr 2025 11:30:45 +0000

What if there were a vitamin that could help treat or prevent prostate cancer? This question has been asked before, with unsettling results. For the Season 2 premiere of our podcast, we sat down At the Lab with CSHL Professor Lloyd Trotman to find out about new preclinical studies that could point to a major...

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Are pro-oxidants anti-prostate cancer?

Communications Department — Tue, 07 Jan 2025 12:30:38 +0000

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Vitamin K supplement slows prostate cancer in mice

Jen A. Miller — Thu, 24 Oct 2024 18:00:34 +0000

Science, shows that menadione significantly slows prostate cancer growth in mice and in human-derived cancer cells, as seen here." data-description="" />Prostate cancer is a quiet killer. In most men, it’s treatable. However, in some cases, it resists all known therapies and turns extremely deadly. A new discovery at ��ϳԹ��Դ (CSHL) points to a potentially groundbreaking solution. CSHL Professor Lloyd Trotman’s lab has found that the pro-oxidant supplement menadione slows prostate cancer progression...

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How does cancer spread? Follow the map

Jen A. Miller — Wed, 25 Sep 2024 11:30:07 +0000

Metastatic cancer can be a devastating diagnosis. The cancer is spreading. It may travel to multiple organs in the body. This could mean more pain and ultimately, death. Unfortunately, just how cancer spreads remains unclear. But now, ��ϳԹ��Դ (CSHL) Professor Adam Siepel and colleagues have a way to better understand that process....

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Cancer has a lot of nerve

Communications Department — Mon, 22 Aug 2022 11:30:51 +0000

« Previous Story Next Story » Manish Vira, a urologist at Northwell Health in New York performs prostate biopsy procedures three to five times a week. He inserts 12 needles into the prostate gland in specific locations, identified by MRI images that reveal malignant or suspicious lesions. The samples then go to a pathologist who...

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The prostate cancer cell that got away

Luis Sandoval — Tue, 16 Nov 2021 16:00:34 +0000

��ϳԹ��Դ (CSHL) Associate Professor Pavel Osten and Professor Lloyd Trotman have developed a new way to study the life history of prostate cancer in mice. The pair combined their expertise in whole-organ imaging and prostate cancer to track how prostate cancer cells grow into tumors and spread to other organs. Their method...

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Fresh insights into prostate cancer surprise Movember crowd

Brian Stallard — Fri, 22 Nov 2019 22:02:22 +0000

crowd of moustached men and women gathered, beers in hand, at Six Harbors Brewing Co. in Huntington, N.Y. They sported handlebars, pencils, chevrons, and rainbow-colored fu manchus. But this wasn’t some meetup for eccentric moustache aficionados. November is Movemeber, men’s health awareness month, and the crowd gathered to hear Dr. Lloyd Trotman speak about prostate...

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Movember with Lloyd Trotman—A Cocktails and Chromosomes talk about prostate cancer

Communications Department — Tue, 19 Nov 2019 21:44:55 +0000

Did you know that 1 in 9 US men will be diagnosed with prostate cancer in their lifetime? But those stats might soon change, thanks to labs like that of Professor Lloyd Trotman. In this special #Movember edition of Cocktails and Chromosomes, learn how modern concepts of cancer evolution could help turn lethal metastatic prostate cancer into a curable disease.

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Enzyme PHLPP2 could be a viable drug target for treating prostate cancer

Charlotte Hu — Wed, 15 May 2019 13:00:54 +0000

Cold Spring Harbor, NY — An estimated 450,000 Americans are diagnosed each year with a cancer that’s driven by MYC, an oncogene that hijacks growth and metabolism in cancer cells. MYC has a storied past of being notoriously hard for researchers to directly disable. “Now, we have a new way of getting at this old...

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One experiment: Observing cancer’s progress in a mouse prostate

Brian Stallard — Thu, 14 Mar 2019 20:16:40 +0000

Experts have long known that tumors arise from the migration of cancer cells across organs. But observing the progression of those cancer cells in high resolution, and in turn being able to more effectively hinder their advances, has been a challenge for scientists. Now, a cutting-edge technique originally developed by Associate Professor Pavel Osten’s lab...

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Study reveals a way to make prostate cancer cells run out of energy and die

Jennifer Michalowski — Tue, 03 Apr 2018 17:00:10 +0000

Cold Spring Harbor, NY — Scientists at ��ϳԹ��Դ (CSHL) have discovered that cells lacking the tumor-suppressor protein PTEN—a feature of many cancers—are particularly vulnerable to drugs that impair their energy-producing mitochondria. Such drugs induce them to literally eat themselves to death, the research shows. Unlike normal cells, cells without PTEN seem driven...

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New method to determine before surgery which prostate tumors pose a lethal threat

Peter Tarr — Fri, 01 Dec 2017 16:38:11 +0000

Prostate cancer is common and largely nonlethal. But for some 21,000 men—a small percentage of the total, but a nonetheless substantial number—the disease is fatal. For earlier and more accurate detection, the Krasnitz and Wigler labs have devised a new method to analyze tumor biopsies to identify the most lethal forms of prostate cancer.

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Researchers identify “Achilles’ heel” of PTEN that helps drive prostate cancer progression

Peter Tarr — Mon, 13 Feb 2017 09:00:41 +0000

New research from the Trotman lab has revealed that, in prostate cancer, a protein known as Importin-11 is the ‘Achilles’ heel’ that is required for the stability of the PTEN tumor suppressor. In fact, loss of Importin-11 predicted relapse and metastasis in patients who had had their prostate removed.

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No (real) moustache required to join the “Movember” party

Andrea Alfano — Tue, 15 Nov 2016 14:54:58 +0000

Prostate cancer is the most common non-skin cancer among American men, but most of the prostate cancer researchers at CSHL have zero risk of developing the disease. he majority of the prostate cancer researchers at CSHL are part of the population that will never get this disease: women. Growing a mo’ for “Movember”—a men’s health...

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Movember: Fighting for health in the Lab and the gym

Andrea Alfano — Fri, 20 Nov 2015 21:14:24 +0000

Even considering that he’s faced pro fighters while training in jiu-jitsu, prostate cancer is by far Dawid Nowak’s most formidable opponent. In the lab of Lloyd Trotman, he’s using an incredibly powerful new genetic engineering tool and an extremely sensitive sequencing technique to take prostate cancer down. n a fight, strategy sometimes proves stronger than brute...

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