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The hitchhiker’s guide to the smelliverse

Communications Department — Tue, 14 Oct 2025 11:30:23 +0000

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A perception quiz to blow your mind

Communications Department — Wed, 26 Mar 2025 11:30:40 +0000

{“questions”:{“7fxb8”:{“id”:”7fxb8″,”mediaType”:”image”,”answerType”:”text”,”imageCredit”:”\u00a9 mh.desing – stock.adobe.com”,”image”:”https:\/\/www.cshl.edu\/wp-content\/uploads\/2024\/08\/mosaic_face_diversity.jpg”,”imageId”:”71410″,”video”:””,”imagePlaceholder”:””,”imagePlaceholderId”:””,”title”:”How long, on average, does it take for the human brain to perceive and respond to visual stimuli?”,”desc”:”Fruit flies can respond to visual stimuli in less than five milliseconds. Our average reaction time is about 200 milliseconds\u2014i.e., one-fifth of a second. Interestingly, this is also about the amount of time that usually...

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Anne Churchland donates $50K prize to CSHL student

Nick Wurm — Wed, 19 Mar 2025 11:30:49 +0000

“I would not have become the scientist I am today were it not for my time at Cold Spring Harbor,” says Anne Churchland. The pioneering neuroscientist has received the National Academy of Sciences (NAS) 2025 Pradel Research Award. Now at the University of California, Los Angeles, Churchland credits her time at ��ϳԹ��Դ...

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A hearing aid for … your nose?

Nick Wurm — Thu, 30 Jan 2025 12:30:56 +0000

AI generated voice with Florin Albeanu’s actual voice Kaboom! The first time most of us hear the sound of an explosion is in the movies. Encountering the sound in the real world—even at a distance—has a profoundly different effect. Why? It’s all about context. How we react to sounds and other sensory stimuli depends on...

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At the Lab Episode 14: What’s that smell?

Communications Department — Tue, 09 Jul 2024 11:30:02 +0000

Smell is often dismissed as somehow less important than our other four senses. But you shouldn’t look down your nose at it. After all, in the wild, it could mean the difference between life and death. This week At the Lab, CSHL Associate Professor Saket Navlakha offers insight into how we learn to distinguish between...

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Smells like learning

Margaret Osborne — Tue, 31 Oct 2023 18:00:33 +0000

Order wine at a fancy restaurant, and the sommelier might describe its aroma as having notes of citrus, tropical fruit, or flowers. Yet, when you take a whiff, it might just smell like … wine. How can wine connoisseurs pick out such similar scents? ��ϳԹ��Դ (CSHL) Associate Professor Saket Navlakha and Salk...

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Follow your nose: Tracking the brain’s smell circuits

Communications Department — Mon, 27 Feb 2023 17:00:55 +0000

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Mapping the path from smell to perception

Jennifer Michalowski — Thu, 27 Oct 2022 15:00:04 +0000

Our sense of smell has a powerful effect on our behavior and emotions. Aromas can evoke vivid memories of the past or warn us of a smoldering fire. Yet to neuroscientists, smell remains the most mysterious of our five senses. Once the nose detects something, how does the brain determine what it means? Scientists aren’t...

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Even fruit flies count

Margaret Osborne — Tue, 25 Oct 2022 11:30:26 +0000

Imagine sitting in your house when you hear a knock on your front door. You peer through the window and see a stranger outside. Almost immediately, your brain knows you’ve never encountered this person before. Maybe you feel scared and pretend you’re not home. Now instead of a stranger, imagine a close friend or family...

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Sniffing out the brain’s smelling power

Luis Sandoval — Thu, 29 Sep 2022 19:00:48 +0000

Since their discovery over 100 years ago, neurons in the brain’s olfactory bulb called tufted cells have been difficult to study. The close proximity between tufted cells and other neurons called mitral cells, restricted the ability to dissect each individual neuron’s activity. By leveraging fluorescent genetic markers and new optical imaging technologies, Cold Spring Harbor...

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The doctor will sniff you now

Communications Department — Mon, 01 Mar 2021 13:30:59 +0000

atlas.brain-map.org." data-description="" />« Previous Story Table of Contents » It’s 2050, and you’re due for your monthly physical exam. Times have changed, so you no longer have to endure an orifices check, a needle in your vein, and a week of waiting for your blood test results. Instead, the nurse welcomes you with, “The doctor will sniff...

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How to tune out common odors and focus on important ones

Brian Stallard — Mon, 11 May 2020 19:00:27 +0000

“Imagine a dog playing in a garden and smelling all of these different flowery smells, and then somewhere in the distance a predator appears, like a fox. The raw input coming into the dog’s nose is a smell that consists of something like 90% flowers and only five or 10% of this predator,” CSHL Associate...

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There’s more to smell than meets the nose

Charlotte Hu — Mon, 22 Jul 2019 18:17:51 +0000

How do animals smell? Scientists haven’t quite decoded it yet, but researchers at ��ϳԹ��Դ (CSHL) have found that it’s different from previously proposed. To understand how the brain processes and interprets smells, CSHL neuroscientists Florin Albeanu, Alexei Koulakov and colleagues are putting past odor classifying models to the test, and they’re discovering...

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Quantifying how the brain smells

Charlotte Hu — Mon, 22 Jul 2019 15:00:05 +0000

Cold Spring Harbor, NY — Scientists haven’t quite decoded how animals smell, but researchers at ��ϳԹ��Դ (CSHL) found that it’s different from previously thought. To understand how the brain processes and interprets smells, CSHL neuroscientists Florin Albeanu, Alexei Koulakov and colleagues Honggoo Chae, Daniel Kepple, Walter Bast from CSHL, and Venkatesh Murthy...

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What’s that smell? Neuroscientists are figuring it out

Sara Roncero-Menendez — Tue, 02 Oct 2018 19:15:31 +0000

��ϳԹ��Դ (CSHL) Associate Professor Florin Albeanu and Professor Alexei Koulakov have received the National Institutes of Health (NIH) Director’s Transformative Research Award for an innovative neuroscience research project on the olfactory system, one of the basic senses that is still quite mysterious. The project will study how the brain interprets smell, an...

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Fantastic journey: how newborn neurons find their proper place in the brain

Peter Tarr — Thu, 02 Nov 2017 12:00:53 +0000

Cold Spring Harbor, NY — One of the most hopeful discoveries of modern neuroscience is firm proof that the human brain is not static following birth. Rather, it is continually renewing itself, via a process called postnatal neurogenesis—literally, the birth of new neurons. It begins not long after birth and continues into old age. There is...

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First direct evidence for synaptic plasticity in fruit fly brain

Communications Department — Wed, 02 Dec 2015 12:00:41 +0000

Cold Spring Harbor, NY — Scientists at ��ϳԹ��Դ (CSHL) have resolved a decades-long debate about how the brain is modified when an animal learns. Using newly developed tools for manipulating specific populations of neurons, the researchers have for the first time observed direct evidence of synaptic plasticity—changes in the strength of connections between...

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Approach or buzz off: Brain cells in fruit fly hold secret to individual odor preferences

Jennifer Michalowski — Tue, 06 Oct 2015 14:38:08 +0000

Responding appropriately to the smell of food or the scent of danger can mean life or death to a fruit fly, and dedicated circuits in the insect’s brain are in place to make sure the fly gets it right. Cold Spring Harbor, NY — Responding appropriately to the smell of food or the scent of...

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Revised view of brain circuit reveals how we avoid being overwhelmed by powerful odors

Peter Tarr — Wed, 01 Jul 2015 12:00:48 +0000

Cold Spring Harbor, NY — You’ve just encountered a frightened skunk, which has sprayed a generous quantity of its sulfur-containing scent directly in your path. The noxious odor is overpowering. As you turn to run in the opposite direction, you are performing with your feet an operation analogous to one that each of your senses...

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New research on what the nose ‘knows’ reveals an unexpected simplicity

Peter Tarr — Sun, 11 Jan 2015 00:00:00 +0000

In rats, olfactory bulb neurons use simple ‘linear summation’ to make sense of fluctuating odor inputs from the surrounding environment Cold Spring Harbor, NY — What the nose knows is quite amazing, when you think about it. The moment you encounter an awful odor—spoiled milk, say, or the scent of skunk—you reflexively recoil in disgust. Often,...

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