Mikala Egeblad Archives | ��ϳԹ��Դ

Borniger reaches Cancer Grand Challenges finals

Samuel Diamond — Wed, 24 Sep 2025 09:00:41 +0000

��ϳԹ��Դ (CSHL) Assistant Professor Jeremy Borniger has been selected for the final stages of a Cancer Grand Challenges research initiative as part of team NEUROIMPACT. The team seeks to determine how the nervous system senses and responds to cancers. In identifying the nervous system’s role in tumor growth and cancer metastasis, they...

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The CSHL School of Biological Sciences’ class of 2025

Communications Department — Mon, 05 May 2025 18:00:58 +0000

The ��ϳԹ��Դ (CSHL) School of Biological Sciences (SBS) takes an innovative approach to advanced science education. Graduates of the doctoral program go on to pursue a wide range of careers. On May 4, the SBS awarded nine graduates Ph.D. degrees. Here, the class of 2025 reflects on their time and experiences at...

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At the Lab Season 1 Research Rewind: Cancer

Communications Department — Tue, 08 Oct 2024 11:30:26 +0000

Miss an episode or two from the first season of our new podcast? Over the next few weeks, we’ll revisit each in a series we call ‘Research Rewind.’ This week At the Lab, you’ll hear all about our cutting-edge cancer research from CSHL scientists Semir Beyaz, Mikala Egeblad, Alea Mills, John Moses, and Christopher Vakoc....

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At the Lab Episode 18: The stress of cancer

Communications Department — Tue, 06 Aug 2024 11:30:42 +0000

In this week’s edition of At the Lab, we sit down with CSHL Adjunct Professor Mikala Egeblad to discuss one of our latest breakthroughs in cancer research. It’s a sobering conversation that should hit close to home for anyone who’s ever been diagnosed with cancer, as well as all of us who have lost loved...

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Women’s health quiz

Communications Department — Tue, 19 Mar 2024 11:30:35 +0000

{“questions”:{“crx1c”:{“id”:”crx1c”,”mediaType”:”image”,”answerType”:”text”,”imageCredit”:”Image: William C. Krause\/Holly Ingraham lab\/University of California, San Francisco”,”image”:”https:\/\/www.cshl.edu\/wp-content\/uploads\/2021\/11\/Tollkuhn_estrogen_sensitive_neurons.jpg”,”imageId”:”56945″,”video”:””,”imagePlaceholder”:””,”imagePlaceholderId”:””,”title”:”Many women naturally become less active as they age and enter menopause. Menopause is brought about by a decline in levels of which hormone?”,”desc”:”CSHL Associate Professor Jessica Tollkuhn and her collaborators identified a group of estrogen-sensitive neurons in the mouse brain that spur movement. The discovery...

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Chronic stress spreads cancer … here’s how

Margaret Osborne — Thu, 22 Feb 2024 16:00:10 +0000

Stress is inevitable. But too much of it can be terrible for our health. Chronic stress can increase our risk for heart disease and strokes. It may also help cancer spread. How this works has remained a mystery—a challenge for cancer care. Xue-Yan He, a former postdoc in ��ϳԹ��Դ (CSHL) Adjunct Professor...

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Dr. Egeblad receives support from the Katie Oppo Research Foundation

Jill Stone — Fri, 30 Sep 2022 19:26:03 +0000

��ϳԹ��Դ’s Dr. Mikala Egeblad has received a $60,000 grant from the Katie Oppo Research Foundation (KORF) to support her work in metastatic ovarian cancer – a disease that is often difficult to treat. In collaboration with Northwell Health, the Egeblad lab is targeting macrophages – a type of immune cells: Macrophages classically have tumor...

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Drug disulfiram prevents immune-related damage

Communications Department — Mon, 14 Feb 2022 17:00:08 +0000

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Drug halts immune reactions to save damaged lungs

Jennifer Michalowski — Tue, 08 Feb 2022 17:00:55 +0000

A team of scientists led by ��ϳԹ��Դ (CSHL) have discovered that disulfiram, an FDA-approved drug, prevents the immune system from producing toxic webs known as neutrophil extracellular traps (NETs). Many scientists suspect NETs help drive the development of acute respiratory distress syndrome (ARDS) in patients with severe COVID-19 and other life-threatening lung...

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Reprogramming the immune response in ovarian cancer

Jill Stone — Fri, 26 Nov 2021 14:00:26 +0000

According to the American Cancer Society, more than 20,000 women are diagnosed with ovarian cancer every year in the U.S. For most of these women, the cancer has already spread to other organs (metastasized) at the time of diagnosis. In addition to malignant cancer cells, tumors are composed of a network of immune cells, blood...

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Can our own immune system fight off cancer?

Communications Department — Wed, 10 Nov 2021 20:00:54 +0000

« Previous Story Next Story » One day in 2010, when oncologist Paul Muizelaar operated on a patient with glioblastoma—a brain tumor infamous for its deathly toll—he did something shocking. First, he cut the skull open and carved out as much of the tumor as he could. But before he replaced the piece of skull...

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Fighting cancer is a rebalancing act

Jasmine Lee — Mon, 01 Nov 2021 15:30:48 +0000

hy do some cancers spread throughout the body? Cancer cells live in a complex neighborhood populated by immune cells, blood vessels, and other structures. Signals crisscross the neighborhood: cells tell each other who is there and what they want. Cancer cells may want to hide their identity or otherwise influence this neighborhood—or microenvironment—so they can...

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Immune cells versus metastatic tumor cells

Eliene Augenbraun — Thu, 02 Sep 2021 20:30:37 +0000

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Research matters

Communications Department — Tue, 08 Jun 2021 18:00:08 +0000

When SARS-CoV-2 (coronavirus) spread throughout the world, 2020 immediately became a historic year. The virus recognized no boundaries; neither physical nor political. Our Cold Spring Harbor Asia conference center employees in Suzhou, China, were the first affected by the pandemic, and soon thereafter, in March, we faced COVID-19 in New York. Like people everywhere, Cold...

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��ϳԹ��Դ: Science is hope

Marc Persad — Mon, 21 Dec 2020 21:03:02 +0000

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Cancer researchers discuss COVID-19’s effect on the field

Sara Roncero-Menendez — Mon, 27 Jul 2020 12:00:38 +0000

Director of the ��ϳԹ��Դ (CSHL) Cancer Center and Roy J. Zuckerberg Professor of Cancer Research David Tuveson and Assistant Professor Tobias Janowitz wrote an editorial in the latest edition of Cancer Discovery. The piece, entitled “The Era of COVID-19 and the Rise of Science Collectivism in Cancer Research”, discusses the active participation...

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How two CSHL programs adapted during the COVID-19 pandemic

Sara Roncero-Menendez — Thu, 16 Jul 2020 20:48:04 +0000

On July 8, ��ϳԹ��Դ (CSHL) Associate Professor Mikala Egeblad and CSHL DNA Learning Center Executive Director David Micklos presented an overview of their research to over 400 digital participants as part of the “Life Science Across the Globe” seminar series. CSHL is one of six sister institutions giving both a science talk...

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How breast cancer cells sneak past local immune defenses

Brian Stallard — Wed, 15 Jul 2020 14:00:17 +0000

��ϳԹ��Դ (CSHL) Associate Professor Mikala Egeblad and her colleagues describe a newly understood way by which breast cancer cells sabotage a key player in the body’s immune system. That key player provides local immune surveillance by activating killer T-cells, but if it cannot mature and do its job, breast cancer cells can...

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CSHL joins “Life Science Across the Globe” seminar series

Sara Roncero-Menendez — Mon, 29 Jun 2020 20:00:59 +0000

��ϳԹ��Դ (CSHL) is joining seven other prominent science institutions from five continents in the “Life Science Across the Globe” (PDF) seminar series. Each institution will give both a science talk and a science culture talk. It is the goal of the series to increase knowledge and advance solutions to global problems through...

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New evidence for how blood clots may form in very ill COVID-19 patients

Jennifer Michalowski — Mon, 29 Jun 2020 14:59:42 +0000

Scientists have new evidence that overactive neutrophils—a common type of circulating immune cell—may drive the life-threatening blood clots and inflammation that occur in some patients with COVID-19. High levels of the sticky, pathogen-trapping webs produced by the cells were associated with the most severe cases of COVID-19 in a study reported online in the journal...

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Mikala Egeblad Archives | ���ϳԹ���Դ