cancer Archives | ��ϳԹ��Դ

CSHL develops endometrial cancer organoid platform

Nick Wurm — Thu, 26 Mar 2026 13:00:21 +0000

More than 68,000 women will be diagnosed with endometrial cancer in 2026. More than 14,000 will die from this condition. While some forms of the disease are treatable, high grade endometrial cancer often resists available immunotherapies. “High grade endometrial cancers (HGEC) are very aggressive,” explains ��ϳԹ��Դ Associate Professor Semir Beyaz. “Even when...

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On the trail of a cellular cold case

Nick Wurm — Tue, 16 Dec 2025 17:00:43 +0000

If you remember high school biology, you know cells pack a lot inside a tiny package. Inside the nucleus of every one of our cells, you’ll see more than a few things floating around. You may be familiar with RNA and DNA. But that’s not all you’ll find there. Over a century ago, scientists discovered...

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Dicer: Life’s ancient repair tool

Nick Wurm — Tue, 28 Oct 2025 15:00:47 +0000

Could yeast and humans be any more different? Going by looks alone, probably not. But peering into our genomes reveals surprising similarities. That’s because we share a common ancestor called LECA (last eukaryotic common ancestor). Before this single-celled organism died off around 2 billion years ago, it passed down Dicer, a key protein humans and...

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BATMAN brings TCR therapy out of the shadows

Nick Wurm — Fri, 25 Jul 2025 15:00:02 +0000

Imagine your immune cells could be modified to attack any kind of cancer. T cell receptor (TCR) therapy has the potential to one day become a universal cancer treatment. But there are risks. Similarities between cancerous and healthy cells can affect the body’s immune response, causing T cells to attack unintended targets. TCR therapy needs...

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A new body of knowledge

Communications Department — Tue, 24 Jun 2025 11:30:00 +0000

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A recipe to reverse cancer’s sweet tooth

Nick Wurm — Mon, 16 Jun 2025 11:30:58 +0000

Sometimes sugar isn’t so sweet. Sometimes, it’s downright deadly. Glycation occurs when an excess of sugars called reducing sugars attach to important proteins in the body. The process has been linked to diabetes and obesity. It’s usually something to avoid, and the body relies on the FN3K kinase to break glycation down. But cancer flips...

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At the Lab: An evening out with the brain and body

Communications Department — Tue, 10 Jun 2025 11:30:28 +0000

Typically, if you hear someone in a bar talking about “conversations” between the brain and the body, you might want to call them a cab. Not this time! Barstool philosophy meets brain-body physiology in our latest At the Lab podcast, featuring audio from CSHL Assistant Professor Jeremy Borniger’s recent Cocktails & Chromosomes talk.

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A CSHL Symposium for the ages

Samuel Diamond — Thu, 05 Jun 2025 11:30:05 +0000

You are not the same person you were a decade ago. Most of your body’s cells are replaced every seven to 10 years. Nevertheless, you retain the genes and memories that help make you, you. Science still doesn’t fully understand how the aging process works. But we’re getting closer, and the answers may hold the...

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At the Lab: The nuclear speckle option

Communications Department — Tue, 06 May 2025 11:30:52 +0000

This week At the Lab, we’re joined by CSHL Assistant Professor Katherine Alexander, the newest member of the ��ϳԹ��Դ faculty. We’ll also hear about a Spanish bodybuilder who’s been dead for more than 90 years. How in the world are these individuals connected? Hit play to hear all about it.

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CSHL holds first-ever cancer neuroscience course

Nick Wurm — Mon, 24 Mar 2025 11:30:47 +0000

The brain controls the body, in large part, through nerves. So, what happens when nerves form new connections with tumors? How does the nervous system drive cancer progression? How do these interactions influence anti-cancer therapies? A burgeoning new field known as cancer neuroscience aims to answer these questions. But how? How does one solve a...

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Cocktails & Chromosomes: The hidden world inside our cells

Communications Department — Thu, 20 Mar 2025 11:30:48 +0000

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Janowitz elected to ASCI

Samuel Diamond — Mon, 27 Jan 2025 12:30:34 +0000

��ϳԹ��Դ Associate Professor Tobias Janowitz has been elected to the American Society for Clinical Investigation (ASCI). Janowitz is recognized for his outstanding scholarly research, which approaches cancer from a whole-body perspective. He has led clinical trials and published authoritative studies on cancer cachexia, a debilitating condition that affects patients in the late...

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From trading faxes to changing lives

Jen A. Miller — Tue, 14 Jan 2025 17:00:40 +0000

Sometimes, scientific breakthroughs happen by accident. Penicillin was discovered when a British scientist left a petri dish uncovered while he was away on vacation. Other times, serendipity plays a role. Case in point: two chance meetings at ��ϳԹ��Դ (CSHL) led to the development of a drug that has vastly improved patient outcomes for...

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Are pro-oxidants anti-prostate cancer?

Communications Department — Tue, 07 Jan 2025 12:30:38 +0000

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A speckle of hope for cancer patients

Luis Sandoval — Thu, 02 Jan 2025 10:00:42 +0000

Nature Cell Biology. " data-description="" />AI generated voice with Kate Alexander’s actual voice Fighting cancer can seem like a deadly game of chance. While some patients may respond well to certain treatments, others might not be as fortunate. Doctors and scientists have long struggled to explain why. Now, ��ϳԹ��Դ (CSHL) Assistant Professor Katherine Alexander and University of...

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CSHL and Range ETFs launch new partnership

Lisa Cruz — Thu, 21 Nov 2024 12:30:49 +0000

More than two million new cases of cancer will be diagnosed in the United States in 2024, according to the National Cancer Institute. Range Cancer Therapeutics ETF (Nasdaq: CNCR) is partnering with ��ϳԹ��Դ (CSHL) to highlight CSHL’s pioneering role in advancing cancer research. Through the partnership, 23% of revenues generated by fees...

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Flipping cancer’s off switch

Communications Department — Thu, 07 Nov 2024 12:30:54 +0000

If there’s one thing cancer knows, it’s growth. Over the last two decades, scientists have observed that many cancers progress by activating a set of proteins called YAP and TAZ, which control cell growth and organ size. When left uncontrolled, YAP/TAZ can lead to tumor formation. So, if you’re looking for new drug targets, why...

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Vitamin K supplement slows prostate cancer in mice

Jen A. Miller — Thu, 24 Oct 2024 18:00:34 +0000

Science, shows that menadione significantly slows prostate cancer growth in mice and in human-derived cancer cells, as seen here." data-description="" />Prostate cancer is a quiet killer. In most men, it’s treatable. However, in some cases, it resists all known therapies and turns extremely deadly. A new discovery at ��ϳԹ��Դ (CSHL) points to a potentially groundbreaking solution. CSHL Professor Lloyd Trotman’s lab has found that the pro-oxidant supplement menadione slows prostate cancer progression...

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At the Lab Season 1 Research Rewind: Cancer

Communications Department — Tue, 08 Oct 2024 11:30:26 +0000

Miss an episode or two from the first season of our new podcast? Over the next few weeks, we’ll revisit each in a series we call ‘Research Rewind.’ This week At the Lab, you’ll hear all about our cutting-edge cancer research from CSHL scientists Semir Beyaz, Mikala Egeblad, Alea Mills, John Moses, and Christopher Vakoc....

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How does cancer spread? Follow the map

Jen A. Miller — Wed, 25 Sep 2024 11:30:07 +0000

Metastatic cancer can be a devastating diagnosis. The cancer is spreading. It may travel to multiple organs in the body. This could mean more pain and ultimately, death. Unfortunately, just how cancer spreads remains unclear. But now, ��ϳԹ��Դ (CSHL) Professor Adam Siepel and colleagues have a way to better understand that process....

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cancer Archives | ���ϳԹ���Դ