Adrian Krainer Archives | ��ϳԹ��Դ

Krainer included in Forbes’ Most Successful Immigrants list

Samuel Diamond — Mon, 15 Jun 2026 11:30:19 +0000

��ϳԹ��Դ (CSHL) Professor Adrian Krainer has been included in Forbes’ list of America’s Most Successful Immigrants. The magazine recognized Krainer for research that “led to the development of Spinraza, the first FDA-approved medicine for spinal muscular atrophy,” and for co-founding biotech company Stoke Therapeutics. After growing up in Uruguay, Krainer came to...

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A fellowship of curiosity

Communications Department — Tue, 26 May 2026 16:00:56 +0000

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Short-circuiting pancreatic cancer

Nick Wurm — Thu, 08 Jan 2026 16:00:45 +0000

Pancreatic ductal adenocarcinoma (PDAC) is the most lethal form of pancreas cancer. It’s also the most common form of the disease. Potential treatments typically target a key mutated oncogene called KRAS. In some cases, PDAC tumors with these mutations have resisted therapeutic efforts. However, combination therapies involving alternative drug targets may one day help clinicians...

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“Philifant” sculpture honors research leading to Spinraza

Nick Wurm — Fri, 29 Aug 2025 14:40:15 +0000

On August 27, pioneering digital artist Phil L. Herold donated a chrome “Philifant” sculpture to ��ϳԹ��Դ (CSHL) for the Krainer lab’s transformative, life-saving research on spinal muscular atrophy (SMA). CSHL Professor Adrian Krainer’s work led to the development of Spinraza, the first FDA-approved treatment for SMA. At the time, the neurodegenerative disease...

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Can you ace this SMA quiz?

Communications Department — Thu, 07 Aug 2025 11:30:37 +0000

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��ϳԹ��Դ hope to thousands of families

Jen A. Miller — Tue, 05 Aug 2025 11:30:41 +0000

It’s a parent’s worst nightmare, finding out your newborn child may never walk or even stand on their own. That used to be the reality for as many as one in 6,000 babies born with spinal muscular atrophy (SMA), a genetic disorder that causes extreme nerve damage, muscle weakness, and sometimes, paralysis. For a long...

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Adrian Krainer wins 2025 Heinrich Wieland Prize

Nick Wurm — Wed, 16 Jul 2025 12:30:07 +0000

��ϳԹ��Դ Professor Adrian Krainer has won the 2025 Heinrich Wieland Prize. Awarded annually by the Boehringer Ingelheim Foundation, the €250,000 prize recognizes exceptional scientists whose pioneering research pushes the boundaries of knowledge in biochemistry, biology, chemistry, and physiology. Krainer received the award for his revolutionary RNA splicing research, which led to the...

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President’s essay: We are science, and science is crucial

Communications Department — Mon, 02 Jun 2025 12:53:01 +0000

At ��ϳԹ��Դ (CSHL), we deeply value our uniquely vibrant campus and culture. But we thrive because we are intensely engaged with the broad community of scientists across the United States and the world. By collaborating, educating, and sharing knowledge, we amplify our impact, enabling groundbreaking discovery at CSHL and beyond. This is...

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2024 Double Helix Medal recipient Dr. Katalin Karikó

Communications Department — Tue, 10 Dec 2024 12:30:20 +0000

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Adrian Krainer wins Albany Prize for biomedical research

Luis Sandoval — Tue, 08 Oct 2024 15:00:21 +0000

��ϳԹ��Դ (CSHL) Professor Adrian Krainer has won the Albany Prize, one of America’s largest awards for biomedical research. He now joins a prestigious list of recipients that includes names like Anthony Fauci, Emmanuelle Charpentier, and Jennifer Doudna. The Albany Prize recognizes scientists whose work has translated from “the bench to the bedside.”...

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RNA splicing’s spotters

Jennifer Michalowski — Mon, 10 Jun 2024 11:30:16 +0000

Bodybuilders and cellular mechanisms agree generating protein is a heavy lift. To complete the task, cells rely on complexes called spliceosomes. These molecular machines snip extra bits out of our genes’ RNA copies and piece together precise instructions for protein-building. When the splicing process goes awry, it can result in diseases like cancer or spinal...

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President’s essay: The continuous cycle of discovery

Communications Department — Thu, 30 May 2024 11:30:43 +0000

��ϳԹ��Դ (CSHL) is a vibrant intellectual community that enables groundbreaking discovery. Our idyllic setting and state-of-the-art facilities offer a uniquely supportive environment for bioscience breakthroughs. However, CSHL’s community is not bound by the geography of our campus. Science worldwide has been strengthened by people who spend time on our campus and by...

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Why some RNA drugs work better than others

Jennifer Michalowski — Wed, 06 Mar 2024 12:30:20 +0000

Spinal muscular atrophy, or SMA, is the leading genetic cause of infant death. Less than a decade ago, ��ϳԹ��Դ (CSHL) Professor Adrian Krainer showed this brutal disease can be treated by tweaking a process called RNA splicing. This breakthrough resulted in Spinraza, the first effective treatment for SMA. It also opened a...

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Laying the groundwork for drug discoveries

Luis Sandoval — Tue, 08 Aug 2023 11:30:01 +0000

Imagine a ��ϳԹ��Դ (CSHL) scientist walks out onto the biotech “Shark Tank” stage to pitch promising biomedical research to venture capitalists. The ask? Millions of dollars. The bait? Life-saving technology. If this kind of cutthroat dealmaking sounds beyond the scope of even the most gifted research scientist, well, it certainly can be....

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Eight serving one: CSHL volleyball mid-season report

Nick Wurm — Wed, 02 Aug 2023 16:00:34 +0000

Breast Friends and P.E. Revival square off during the 2022 Volleyball League Championship. The regular season runs from July through August, leading up to a best-of-three final in September." data-description="" />��ϳԹ��Դ’s (CSHL’s) 32nd annual Volleyball League season is in full swing. Eight teams sit at the midway point of a quest to capture the coveted Tiernan Cup and a year’s worth of bragging rights. Only a few short weeks remain before the playoffs. Returning champions Breast Friends, led by Marygrace Trousdell and...

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Adrian Krainer awarded honorary IADR membership

Nick Wurm — Wed, 21 Jun 2023 23:00:43 +0000

��ϳԹ��Դ Professor Adrian Krainer has been named an honorary member of the International Association for Dental Research (IADR) for 2023. The IADR honored Krainer for fundamental and translational research that led to a life-saving treatment for spinal muscular atrophy (SMA). The group also acknowledged him for “enhancing our understanding of how [RNA]...

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President’s essay: Bringing bold visions to life

Communications Department — Fri, 26 May 2023 11:30:08 +0000

The art of high-impact research, which is at the core of ��ϳԹ��Դ (CSHL), is to pursue important questions, follow unanticipated leads, and be bold in crafting new ideas. In this way, we challenge our researchers to move science into new frontiers. While our scientists have freedom to pursue their ideas, they are...

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This killer protein causes pancreatic cancer

Nick Wurm — Wed, 26 Apr 2023 14:00:26 +0000

Pancreatic ductal adenocarcinoma (PDAC) is the most common form of pancreatic cancer. It’s also one of the deadliest. More than 90% of PDAC patients die within five years of diagnosis. Usually, by the time the cancer is identified, it has already spread. “PDAC is often found too late for treatments like chemotherapy and surgery to...

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Krainer named Society for RNA Therapeutics board member

Samuel Diamond — Tue, 18 Apr 2023 11:30:59 +0000

If RNA therapeutics were once considered the future of medicine, that future is now. Studies suggest RNA-based treatments have saved tens of millions of lives over the past few years. Now, the newly formed Society for RNA Therapeutics has come together to help further this cutting-edge science. On April 10, ��ϳԹ��Դ Professor...

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From tragedy, a potential pediatric cancer treatment

Nick Wurm — Wed, 12 Apr 2023 18:00:35 +0000

Diffuse intrinsic pontine glioma (DIPG) is a lethal pediatric brain cancer that often kills within a year of diagnosis. Surgery is almost impossible because of the tumors’ location. Chemotherapy has debilitating side effects. New treatment options are desperately needed. ��ϳԹ��Դ Professor Adrian Krainer is best known for his groundbreaking research on antisense...

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Adrian Krainer Archives | ���ϳԹ���Դ