Research Highlights

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Hundreds of scientists working at ��ϳԹ��Դ contribute research published in major research journals, in the fields of Cancer, Neuroscience, Plant Biology, Quantitative Biology, and Genomics.

Immune cells sculpt circuits in the brain

9/14/2020

Immune cells play an unexpected role in fine-tuning the brain’s neural circuits. Read the story »

an image of a section of mouse brain stained to show the insomnia

Stress, sleep, and immunity

9/9/2020

Researchers found the brain circuit that connects stress-induced insomnia and the immune system in mice. Read the story »

Understanding the inner workings of the human heart

8/19/2020

Scientists show that muscular structures first described by Leonardo da Vinci are essential for heart function. Read the story »

How to map brain connections using DNA barcodes

7/14/2020

A new technique labels brain cells with short snippets of DNA to trace many neuronal connections at a time. Read the story »

Pregnancy reprograms breast cells, reducing cancer risk

5/27/2020

CSHL researchers discovered that pregnancy reprograms breast cells, reducing the risk of breast cancer in women under 25. Read the story »

photo of Justin Kinney pointing to a model of an artificial neural network on his tablet

Finally, machine learning interprets gene regulation clearly

12/26/2019

Machine learning and a new kind of easily-interpretable artificial neural network is helping scientists make sense of crucial gene regulation. Read the story »

Shifting the balance of growth vs. defense boosts crop yield

12/19/2019

Researchers found that a specific gene in maize balances both growth of the plant and its immunity. Read the story »

BARseq builds a better brain map

10/17/2019

Created by CSHL neuroscientists, BARseq is capable of mapping connections within a brain at single-neuron resolution while tracing their gene expression. Read the story »

Mutant cells team up to make an even deadlier blood cancer

10/2/2019

Two very different mutations have been identified as unexpected partners-in-crime for causing the deadly blood cancer acute myeloid leukemia. Read the story »

Discovery could improve MDS cancer treatment

9/25/2019

Researchers have discovered a promising new target for treating myelodysplastic syndrome (MDS), a common and lethal blood cancer. Read the story »

Mice, like humans, fidget when deep in thought

9/24/2019

Mice seemed to fidget while making decisions, prompting neuroscientists to think more about the connection between movement and cognition. Read the story »

image of mitral cells and position chart

Quantifying how the brain smells

7/22/2019

Neuroscience researchers at CSHL are trying to figure out how the brain processes smells and what features of odors are important in that process. Read the story »

Norovirus structures could help develop treatments for food poisoning

6/11/2019

Researchers at CSHL used cryo-EM to reconstruct the structures of four different strains of human noroviruses, which cause food poisoning. Read the story »

image of brain mapped neural connections

Detailed new primate brain atlas could lead to disease insights

3/1/2019

An international effort has mapped the marmoset brain at an unprecedented level of detail, which brings us closer to understanding the human brain. Read the story »

image of NMDA receptor binding with chemical compound

Targeting ‘hidden pocket’ for treatment of stroke and seizure

1/18/2019

Researchers have identified a hidden molecular “pocket” in a special neuron receptor, which could lead to better treatments for stroke and seizures. Read the story »

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