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Zachary Lippman

Zachary Lippman

Professor & HHMI Investigator
Jacob Goldfield Professor of Genetics
Director of Graduate Studies

Ph.D., Watson School of Biological Sciences at 黑料吃瓜资源, 2004

[email protected] | 516-367-8897

 

My research team studies when and where, and how many branches, flowers, and fruits are produced on plants. All of plant development depends on small groups of stem cells at the tips of shoots known as meristems. By studying the genes that control stem cell production and maturation over space and time, within and between different developmental contexts, we are able to manipulate plant architecture and reproduction to improve crop yields.

Zachary Lippman鈥檚 research program integrates development, genetics, genomics, and genome editing to uncover, explore, and exploit the mechanisms that determine how plant stem cells become shoots and flowers. The lab takes advantage of extensive natural and engineered genetic variation that influence vegetative and inflorescence production and architecture in tomato and related nightshade (Solanaceae) species (e.g. potato, pepper, groundcherry) to explore how differences in these processes explain the remarkable diversity in the architectures of these shoot systems found in nature and agriculture. Recent discoveries on the genes and networks underlying this diversity have led to broader questions on the significance of genomic structural variation, genetic redundancy, gene dosage, and epistasis in development, evolution, domestication, and breeding. By linking these fundamental and applied discoveries, Lippman is developing and applying innovative concepts and tools to accelerate crop improvement.

Zachary Lippman wins Charles Albert Shull Award
Lippman wins NAS Prize in Food and Agriculture Sciences
Zachary Lippman named 2019 MacArthur Fellow
Prof. Zachary Lippman named Blavatnik Award finalist
CSHL鈥檚 Zachary Lippman named HHMI Investigator
Harold M. Weintraub awardee

See all Lippman news

All Publications

19 Aug 2025 | bioRxiv
Domingo, Miguel;  Fitzgerald, Blaine;  Robitaille, Gina;  Ramakrishnan, Srividya;  Swartwood, Kerry;  Karavolias, Nicholas;  Schatz, Michael;  Van Eck, Joyce;  Lippman, Zachary;  

9 Jul 2025 | Nature
Zebell, Sophia;  Martí-Gómez, Carlos;  Fitzgerald, Blaine;  Cunha, Camila;  Lach, Michael;  Seman, Brooke;  Hendelman, Anat;  Sretenovic, Simon;  Qi, Yiping;  Bartlett, Madelaine;  Eshed, Yuval;  McCandlish, David;  Lippman, Zachary;  

2025 | bioRxiv
Gentile, Iacopo;  Santo Domingo, Miguel;  Zebell, Sophia;  Fitzgerald, Blaine;  Lippman, Zachary;  

3 May 2025 | bioRxiv
Swartwood, Kerry;  Green, Yumi;  Gentile, Iacopo;  Lippman, Zachary;  Van Eck, Joyce;  

5 Mar 2025 | Nature
Benoit, Matthias;  Jenike, Katharine;  Satterlee, James;  Ramakrishnan, Srividya;  Gentile, Iacopo;  Hendelman, Anat;  Passalacqua, Michael;  Suresh, Hamsini;  Shohat, Hagai;  Robitaille, Gina;  Fitzgerald, Blaine;  Alonge, Michael;  Wang, Xingang;  Santos, Ryan;  He, Jia;  Ou, Shujun;  Golan, Hezi;  Green, Yumi;  Swartwood, Kerry;  Karavolias, Nicholas;  Sierra, Gina;  Orejuela, Andres;  Roda, Federico;  Goodwin, Sara;  McCombie, W;  Kizito, Elizabeth;  Gagnon, Edeline;  Knapp, Sandra;  Särkinen, Tiina;  Frary, Amy;  Gillis, Jesse;  Van Eck, Joyce;  Schatz, Michael;  Lippman, Zachary;  

25 Feb 2025 | Proceedings of the National Academy of Sciences of the United States of America | 122(8):e2421990122
Lanctot, Amy;  Hendelman, Anat;  Udilovich, Peter;  Robitaille, Gina;  Lippman, Zachary;  

25 Feb 2025 | bioRxiv
Zebell, Sophia;  Martí-Gómez, Carlos;  Fitzgerald, Blaine;  Pinto Da Cunha, Camila;  Lach, Michael;  Seman, Brooke;  Hendelman, Anat;  Sretenovic, Simon;  Qi, Yiping;  Bartlett, Madelaine;  Eshed, Yuval;  McCandlish, David;  Lippman, Zachary;  

5 Nov 2024 | bioRxiv
Lanctot, Amy;  Hendelman, Anat;  Udilovich, Peter;  Robitaille, Gina;  Lippman, Zachary;  

14 Sep 2024 | bioRxiv
Benoit, Matthias;  Jenike, Katharine;  Satterlee, James;  Ramakrishnan, Srividya;  Gentile, Iacopo;  Hendelman, Anat;  Passalacqua, Michael;  Suresh, Hamsini;  Shohat, Hagai;  Robitaille, Gina;  Fitzgerald, Blaine;  Alonge, Michael;  Wang, Xingang;  Santos, Ryan;  He, Jia;  Ou, Shujun;  Golan, Hezi;  Green, Yumi;  Swartwood, Kerry;  Sierra, Gina;  Orejuela, Andres;  Fornaguera, Federico;  Goodwin, Sara;  McCombie, William;  Kizito, Elizabeth;  Gagnon, Edeline;  Knapp, Sandra;  Sarkinen, Tiina;  Frary, Amy;  Gillis, Jesse;  Van Eck, Joyce;  Schatz, Michael;  Lippman, Zachary;  

2 Aug 2024 | Science | 385(6708):eado1663
Satterlee, James;  Alonso, David;  Gramazio, Pietro;  Jenike, Katharine;  He, Jia;  Arrones, Andrea;  Villanueva, Gloria;  Plazas, Mariola;  Ramakrishnan, Srividya;  Benoit, Matthias;  Gentile, Iacopo;  Hendelman, Anat;  Shohat, Hagai;  Fitzgerald, Blaine;  Robitaille, Gina;  Green, Yumi;  Swartwood, Kerry;  Passalacqua, Michael;  Gagnon, Edeline;  Hilgenhof, Rebecca;  Huggins, Trevis;  Eizenga, Georgia;  Gur, Amit;  Rutten, Twan;  Stein, Nils;  Yao, Shengrui;  Poncet, Adrien;  Bellot, Clement;  Frary, Amy;  Knapp, Sandra;  Bendahmane, Mohammed;  Särkinen, Tiina;  Gillis, Jesse;  Van Eck, Joyce;  Schatz, Michael;  Eshed, Yuval;  Prohens, Jaime;  Vilanova, Santiago;  Lippman, Zachary;