Huiqing (Ching) Zhan
Research Assistant Professor
Ph.D., National University of Singapore, 2009
[email protected] | 516-367-5083
MAPseq and BARseq are two novel high-throughput, multiplexed methods for brain mapping and in situ transcriptomics. Our goal is to develop and optimize these new techniques and apply them to the broader neuroscience community.
Traditional neuroanatomical approaches at single-cell resolution are expensive and labor-intensive. MAPseq and BARseq are two novel high-throughput techniques by converting neuroanatomy into a problem of DNA sequencing. By barcoding each neuron, we can overcome the conventional limit and exploit the throughput of next-generation sequencing in neuroanatomy. BARseq also helps bridge anatomical and transcriptomic approaches at subcellular spatial resolution. I and my team aim to develop and optimize MAPseq/BARseq techniques and provide collaborative research support to the broader research community.
Selected Publications
18 Oct 2023 | Neuron | 111(20):3307-3320.e5
Zeisler, Zachary; London, Liza; Janssen, William; Fredericks, J; Elorette, Catherine; Fujimoto, Atsushi; Zhan, Huiqing; Russ, Brian; Clem, Roger; Hof, Patrick; Stoll, Frederic; Rudebeck, Peter;  
27 Oct 2022 | Cell | 185(22):4117-4134.e28
Chen, Yushu; Chen, Xiaoyin; Baserdem, Batuhan; Zhan, Huiqing; Li, Yan; Davis, Martin; Kebschull, Justus; Zador, Anthony; Koulakov, Alexei; Albeanu, Dinu;  
12 Oct 2022 | Journal of Neuroscience | 42(41):7733-7743
Hausmann, Frances; Barrett, John; Martin, Megan; Zhan, Huiqing; Shepherd, Gordon;  
10 May 2021 | Nature Neuroscience
Sun, Yu-Chi; Chen, Xiaoyin; Fischer, Stephan; Lu, Shaina; Zhan, Huiqing; Gillis, Jesse; Zador, Anthony;  
17 Oct 2019 | Cell | 179(3):772-786.e19
Chen, X; Sun, Y; Zhan, H; Kebschull, J; Fischer, S; Matho, K; Huang, Z; Gillis, J; Zador, A;  
All Publications
27 Sep 2024 | Nature Communications | 15(1):8371
Yuan, Li; Chen, Xiaoyin; Zhan, Huiqing; Henry, Gilbert; Zador, Anthony;  
14 Sep 2024 | bioRxiv
Banerjee, Arkarup; Isko, Emily; Harpole, Clifford; Zheng, Xiaoyue; Zhan, Huiqing; Davis, Martin; Zador, Anthony;  
20 Feb 2023 | bioRxiv
Zeisler, Zachary; London, Liza; Janssen, William; Fredericks, J; Elorette, Catherine; Fujimoto, Atsushi; Zhan, Huiqing; Russ, Brian; Clem, Roger; Hof, Patrick; Stoll, Frederic; Rudebeck, Peter;  
18 Feb 2023 | bioRxiv
Yuan, Li; Chen, Xiaoyin; Zhan, Huiqing; Gilbert, Henry; Zador, Anthony;  
Oct 2021 | Nature | 598(7879):159-166
Muñoz-Castañeda, Rodrigo; Zingg, Brian; Matho, Katherine; Chen, Xiaoyin; Wang, Quanxin; Foster, Nicholas; Li, Anan; Narasimhan, Arun; Hirokawa, Karla; Huo, Bingxing; Bannerjee, Samik; Korobkova, Laura; Park, Chris; Park, Young-Gyun; Bienkowski, Michael; Chon, Uree; Wheeler, Diek; Li, Xiangning; Wang, Yun; Naeemi, Maitham; Xie, Peng; Liu, Lijuan; Kelly, Kathleen; An, Xu; Attili, Sarojini; Bowman, Ian; Bludova, Anastasiia; Cetin, Ali; Ding, Liya; Drewes, Rhonda; D'Orazi, Florence; Elowsky, Corey; Fischer, Stephan; Galbavy, William; Gao, Lei; Gillis, Jesse; Groblewski, Peter; Gou, Lin; Hahn, Joel; Hatfield, Joshua; Hintiryan, Houri; Huang, Junxiang; Kondo, Hideki; Kuang, Xiuli; Lesnar, Philip; Li, Xu; Li, Yaoyao; Lin, Mengkuan; Lo, Darrick; Mizrachi, Judith; Mok, Stephanie; Nicovich, Philip; Palaniswamy, Ramesh; Palmer, Jason; Qi, Xiaoli; Shen, Elise; Sun, Yu-Chi; Tao, Huizhong; Wakemen, Wayne; Wang, Yimin; Yao, Shenqin; Yuan, Jing; Zhan, Huiqing; Zhu, Muye; Ng, Lydia; Zhang, Li; Lim, Byung; Hawrylycz, Michael; Gong, Hui; Gee, James; Kim, Yongsoo; Chung, Kwanghun; Yang, X; Peng, Hanchuan; Luo, Qingming; Mitra, Partha; Zador, Anthony; Zeng, Hongkui; Ascoli, Giorgio; Josh Huang, Z; Osten, Pavel; Harris, Julie; Dong, Hong-Wei;