Erika Tse-Luen Wee
Research Assistant Professor & Director, Microscopy Shared Resource
Ph.D., National Tsing Hua University, 2009
[email protected] | 516-367-5079
Develop and implement state-of-the-art fluorescence imaging and analysis techniques to quantify cell and tissue samples' structure and function.
Develop and implement state-of-the-art fluorescence imaging and analysis techniques to quantify the molecular and cellular mechanisms of cell and tissue function to provide insights into cancer, neuroscience, and plant biology. Investigate the dynamic intricacies of cell-cell interactions, protein localization, and signaling using innovative imaging techniques. Train individuals in using advanced microscope modalities and advise researchers on the preparation of live cells, organoids, and tissue sections for advanced high-resolution 3D tissue imaging, and 4D live cell imaging to localize protein-protein and protein-nucleic-acid interactions and examine intra-cellular/tissue structures. Provide training and support for advanced software packages for advanced image processing, 3D rendering, and 4D measurements.
Selected Publications
5 Apr 2023 | Microscopy and Microanalysis | 29(2):616-634
Abrams, Benjamin; Pengo, Thomas; Wee, Tse-Luen; Deagle, Rebecca; Vuillemin, Nelly; Callahan, Linda; Smith, Megan; Kubow, Kristopher; Girard, Anne-Marie; Rappoport, Joshua; Bayles, Carol; Cameron, Lisa; Cole, Richard; Brown, Claire;  
28 Sep 2022 | Nature Neuroscience
Auguste, Yohan; Ferro, Austin; Kahng, Jessica; Xavier, Andre; Dixon, Jessica; Vrudhula, Uma; Nichitiu, Anne-Sarah; Rosado, Daniele; Wee, Tse-Luen; Pedmale, Ullas; Cheadle, Lucas;  
16 Nov 2021 | Cell Reports | 37(7):110027
Taranda, Julian; Mathew, Grinu; Watrud, Kaitlin; El-Amine, Nour; Lee, Matthew; Elowsky, Corey; Bludova, Anastasiia; Escobar Avelar, Sintia; Nowak, Dawid; Wee, Tse-Luen; Wilkinson, John; Trotman, Lloyd; Osten, Pavel;  
7 Aug 2019 | Scientific Reports | 9(1):11430
Rajah, Abira; Boudreau, Colton; Ilie, Alina; Wee, Tse-Luen; Tang, Kaixi; Borisov, Aleksandar; Orlowski, John; Brown, Claire;  
All Publications
28 Nov 2024 | Nature Communications | 15(1):10364
Song, Dongyan; Cen, Yuxin; Qian, Zhe; Wu, Xiaoli; Rivera, Keith; Wee, Tse-Luen; Demerdash, Osama; Chang, Kenneth; Pappin, Darryl; Vakoc, Christopher; Tonks, Nicholas;  
25 Oct 2024 | Science | 386(6720):eadk9167
Swamynathan, Manojit; Kuang, Shan; Watrud, Kaitlin; Doherty, Mary; Gineste, Charlotte; Mathew, Grinu; Gong, Grace; Cox, Hilary; Cheng, Eileen; Reiss, David; Kendall, Jude; Ghosh, Diya; Reczek, Colleen; Zhao, Xiang; Herzka, Tali; Špokait臈, Saul臈; Dessus, Antoine; Kim, Seung; Klingbeil, Olaf; Liu, Juan; Nowak, Dawid; Alsudani, Habeeb; Wee, Tse-Luen; Park, Youngkyu; Minicozzi, Francesca; Rivera, Keith; Almeida, Ana; Chang, Kenneth; Chakrabarty, Ram; Wilkinson, John; Gimotty, Phyllis; Diermeier, Sarah; Egeblad, Mikala; Vakoc, Christopher; Locasale, Jason; Chandel, Navdeep; Janowitz, Tobias; Hicks, James; Wigler, Michael; Pappin, Darryl; Williams, Roger; Cifani, Paolo; Tuveson, David; Laporte, Jocelyn; Trotman, Lloyd;  
14 Sep 2024 | bioRxiv
Gomez, Adrian; Wu, Yue; Zhang, Chao; Boyd, Leah; Wee, Tse-Luen; Gewolb, Joseph; Amor, Corina; Cheadle, Lucas; Borniger, Jeremy;  
26 Jul 2024 | Cancer Discovery
Klingbeil, Olaf; Skopelitis, Damianos; Tonelli, Claudia; Yoshimoto, Toyoki; Alpsoy, Aktan; Panepinto, Maria; Minicozzi, Francesca; Merrill, Joseph; Cafiero, Amanda; Aggarwal, Disha; Russo, Suzanne; Ha, Taehoon; Demerdash, Osama; Wee, Tse-Luen; Spector, David; Lyons, Scott; Tuveson, David; Cifani, Paolo; Vakoc, Christopher;  
2024 | Proceedings of the National Academy of Sciences of the United States of America | 121(30)
Segovia, Danilo; Adams, Dexter; Hoffman, Nickolas; Tepes, Polona; Wee, Tse-Luen; Cifani, Paolo; Joshua-Tor, Leemor; Krainer, Adrian;  
21 May 2024 | Proceedings of the National Academy of Sciences of the United States of America | 121(21):e2322974121
Segovia, Danilo; Adams, Dexter; Hoffman, Nickolas; Safaric Tepes, Polona; Wee, Tse-Luen; Cifani, Paolo; Joshua-Tor, Leemor; Krainer, Adrian;