Corina Amor Vegas
Assistant Professor
Cancer Center Program Co-Leader
M.D., Ph.D., Gerstner Sloan Kettering Graduate School of Biomedical Sciences, 2021
[email protected] | 516-367-5504
As we age our body accumulates damaged 鈥渟enescent鈥 cells that our immune system is no longer able to effectively eliminate. Senescent cells are responsible for the development of aging and age-related diseases like cancer or fibrosis. My group studies how senescent cells evade the immune system thereby identifying new therapeutic approaches.
Our lab studies cellular senescence. Senescence is a stress response program that is triggered in damaged cells and leads to their elimination by the immune system. If uncleared, the accumulation of senescent cells generates a chronic pro-inflammatory microenvironment that conduces to aging and tumor development. We seek to understand how the immune system recognizes and targets these cells in physiological conditions and how senescent cells evade immune clearance in disease. We aim to leverage our findings to develop immune-based therapeutic approaches to target senescent cells in cancer, aging and age-related pathologies. In our studies we develop and combine novel somatic mouse models of cancer and cell-based therapeutics such as our recently developed senolytic CAR T cells.
Meet the School of Biological Sciences Class of 2026
May 7, 2026
This year鈥檚 six Ph.D. recipients reflect on their time and experiences at CSHL.
Corina Amor Vegas awarded $750K MIND Prize
March 10, 2026
The Pershing Square Foundation award will fund research aimed at developing CAR T cell therapies for Alzheimer鈥檚 disease.
Gut health 脿 la CAR T
December 11, 2025
Wouldn鈥檛 you like to be able to eat the way you did when you were younger? A one-dose treatment could help rejuvenate and regenerate the intestines.
Her science could help you live healthier, longer
November 17, 2025
Could 60 be the new 40? At 黑料吃瓜资源, cellular biologist Corina Amor Vegas鈥 research rewinds the clock on health and disease.
The 10th annual CSHL Raft Race
October 1, 2025
The Raft Race is an annual showcase of the CSHL community鈥檚 creative, ingenious, and competitive spirit.
Amor Vegas named 2025 HHMI Freeman Hrabowski Scholar
September 29, 2025
Amor Vegas was recognized for pioneering research on senescence and immune response, which may lead to new treatments for aging-related conditions.
Zombie cells: The intersection of cancer and aging
July 1, 2025
These zombies have more to say than just 鈥渂rains.鈥 Let's see what they might tell us about the secrets of youth, rejuvenation, health, and disease.
The 2024 CSHL Raft Race
November 12, 2024
Ten teams brave cool harbor waters, the hot August sun, and new boat-building rules in the 9th annual CSHL Raft Race.
CSHL鈥檚 oldest haunts
October 31, 2024
These buildings have weathered oceans of time to be here. Pull back the veil and cross over into CSHL鈥檚 storied past for a closer look.
23rd Annual Women鈥檚 Partnership for Science raises over $360,000
October 10, 2024
CSHL's 23rd annual Women鈥檚 Partnership for Science Lecture and Luncheon raised over $360,000 for scientific research.
All Publications
29 Jul 2025 | Proceedings of the National Academy of Sciences of the United States of America | 122(30):e2424286122
Boyer, Jacob; Rosen, Ezra; Sharma, Malvika; Dorso, Madeline; Mai, Nicholas; Amor, Corina; Reiter, Jason; Kannan, Ram; Gadal, Sunyana; Xu, Jianing; Miele, Matthew; Li, Zhuoning; Chen, Xiaoping; Chang, Qing; Pareja, Fresia; Worland, Stephan; Warner, Douglas; Sperry, Sam; Chiang, Gary; Thompson, Peggy; Yang, Guangli; Ouerfelli, Ouathek; Drilon, Alexander; de Stanchina, Elisa; Wendel, Hans-Guido; Chandarlapaty, Sarat; Rosen, Neal;
28 May 2025 | Genes & Development
Fernández Maestre, Inés; Harris, Alexander; Amor, Corina;
28 Sep 2024 | Cell Death and Disease | 15(9):694
Murga, Matilde; Lopez-Pernas, Gema; Soliva, Robert; Fueyo-Marcos, Elena; Amor, Corina; Faustino, Ignacio; Serna, Marina; Serrano, Alicia; Díaz, Lucía; Martínez, Sonia; Blanco-Aparicio, Carmen; Antón, Marta; Seashore-Ludlow, Brinton; Pastor, Joaquín; Jafari, Rozbeh; Lafarga, Miguel; Llorca, Oscar; Orozco, Modesto; Fernández-Capetillo, Oscar;
14 Sep 2024 | bioRxiv
Gomez, Adrian; Wu, Yue; Zhang, Chao; Boyd, Leah; Wee, Tse-Luen; Gewolb, Joseph; Amor, Corina; Cheadle, Lucas; Borniger, Jeremy;
10 Jun 2024 | Nature Aging
Guo, Guangran; Amor, Corina;
11 May 2024 | bioRxiv
Boyer, Jacob; Sharma, Malvika; Dorso, Madeline; Mai, Nicholas; Amor, Corina; Reiter, Jason; Kannan, Ram; Gadal, Sunyana; Xu, Jianing; Miele, Matthew; Zhuoning, Li; Chen, Xiaoping; Chang, Qing; Pareja, Fresia; Worland, Stephan; Warner, Douglas; Sperry, Sam; Chiang, Gary; Thompson, Peggy; Yang, Guangli; Ouerfelli, Ouathek; De Stanchina, Elisa; Wendel, Hans; Rosen, Ezra; Chandarlapaty, Sarat; Rosen, Neal;
22 Mar 2024 | bioRxiv
Eskiocak, Onur; Chowdhury, Saria; Shah, Vyom; Nnuji-John, Emmanuella; Chung, Charlie; Boyer, Jacob; Harris, Alexander; Habel, Jill; Sadelain, Michel; Beyaz, Semir; Amor, Corina;
Mar 2024 | Nature | 627(8004):E9
Amor, Corina; Feucht, Judith; Leibold, Josef; Ho, Yu-Jui; Zhu, Changyu; Alonso-Curbelo, Direna; Mansilla-Soto, Jorge; Boyer, Jacob; Li, Xiang; Giavridis, Theodoros; Kulick, Amanda; Houlihan, Shauna; Peerschke, Ellinor; Friedman, Scott; Ponomarev, Vladimir; Piersigilli, Alessandra; Sadelain, Michel; Lowe, Scott;
18 Mar 2024 | Journal of Hepatology | :S0168-8278(24)00197
Yashaswini, Chittampalli; Qin, Tianyue; Bhattacharya, Dipankar; Amor, Corina; Lowe, Scott; Lujambio, Amaia; Wang, Shuang; Friedman, Scott;
24 Jan 2024 | Nature Aging
Amor, Corina; Fernández-Maestre, Inés; Chowdhury, Saria; Ho, Yu-Jui; Nadella, Sandeep; Graham, Courtenay; Carrasco, Sebastian; Nnuji-John, Emmanuella; Feucht, Judith; Hinterleitner, Clemens; Barthet, Valentin; Boyer, Jacob; Mezzadra, Riccardo; Wereski, Matthew; Tuveson, David; Levine, Ross; Jones, Lee; Sadelain, Michel; Lowe, Scott;