Luis Sandoval, Author at ��ϳԹ��Դ

A speckle of hope for cancer patients

Luis Sandoval — Thu, 02 Jan 2025 10:00:42 +0000

Nature Cell Biology. " data-description="" />AI generated voice with Kate Alexander’s actual voice Fighting cancer can seem like a deadly game of chance. While some patients may respond well to certain treatments, others might not be as fortunate. Doctors and scientists have long struggled to explain why. Now, ��ϳԹ��Դ (CSHL) Assistant Professor Katherine Alexander and University of...

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Great minds think AI

Luis Sandoval — Wed, 16 Oct 2024 11:30:49 +0000

What if there was a tiny drone whose in-flight controls were modeled on the visual capabilities of the common fruit fly? What if individual neurons in the human brain were sensitive to speech context? Yesterday’s flights of fancy are today’s emerging discoveries as leading scientists from around the world gather at ��ϳԹ��Դ...

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Adrian Krainer wins Albany Prize for biomedical research

Luis Sandoval — Tue, 08 Oct 2024 15:00:21 +0000

��ϳԹ��Դ (CSHL) Professor Adrian Krainer has won the Albany Prize, one of America’s largest awards for biomedical research. He now joins a prestigious list of recipients that includes names like Anthony Fauci, Emmanuelle Charpentier, and Jennifer Doudna. The Albany Prize recognizes scientists whose work has translated from “the bench to the bedside.”...

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The curious immune cells caught between worlds

Luis Sandoval — Tue, 24 Sep 2024 15:00:58 +0000

Our immune system spans two worlds—innate and adaptive. Innate immune cells are like troops at the gate ready to hold off invaders and raise the body’s alarms. Adaptive immune cells are specialists that take longer to respond but can fight off foes in a more targeted manner. Curiously, there are also immune cells that exist...

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Is CREME AI’s answer to CRISPR?

Luis Sandoval — Mon, 16 Sep 2024 09:00:02 +0000

Imagine you’re looking at millions upon millions of mysterious genetic mutations. With CRISPR gene-editing technology, a select few of these mutations might have therapeutic potential. However, proving it would mean many thousands of hours of lab work. Just figuring out which ones are worth exploring further would take a lot of time and money. But...

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Katherine Alexander joins CSHL cancer faculty

Luis Sandoval — Mon, 05 Aug 2024 11:30:35 +0000

The nucleus is a central cellular compartment famous for housing DNA. But it also harbors a collection of lesser-known structures called nuclear speckles. “If the nucleus is a lake filled with DNA, the speckles are 30 to 50 islands intermingled inside that lake of different shapes, sizes, and textures,” says ��ϳԹ��Դ’s (CSHL’s)...

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This protein does “The Twist”

Luis Sandoval — Wed, 31 Jul 2024 15:00:56 +0000

Proteins are constantly performing a kind of dance. They move and contort their bodies to fulfill specific functions inside our bodies. The NMDAR protein executes an especially hard dance routine in our brains. One wrong step can lead to a range of neurological disorders. NMDAR binds to the neurotransmitter, glutamate, and another compound, glycine. These...

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Recapping CSHL’s 88th Symposium

Luis Sandoval — Wed, 10 Jul 2024 11:45:39 +0000

We tend to regard the brain as a kind of thinking machine—an advanced computer that takes in data in the form of sensory information and spits it back out as communication or behavior. But it’s much more than that. The brain is a hub for numerous bodily processes, including metabolism, sleep, and immune response. How...

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Finding the sweet spot in brain development

Luis Sandoval — Mon, 01 Jul 2024 11:30:23 +0000

Not everything in the brain is meant to last. As our brains assemble, trillions of neural connections have to be built or torn down at the right time and place. Otherwise, the seeds of disorders like autism can take root. ��ϳԹ��Դ Assistant Professor Gabrielle Pouchelon studies how the brain is wired early...

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SQUID pries open AI black box

Luis Sandoval — Fri, 21 Jun 2024 09:00:16 +0000

Artificial intelligence continues to squirm its way into many aspects of our lives. But what about biology, the study of life itself? AI can sift through hundreds of thousands of genome data points to identify potential new therapeutic targets. While these genomic insights may appear helpful, scientists aren’t sure how today’s AI models come to...

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Can AI learn like us?

Luis Sandoval — Thu, 20 Jun 2024 11:30:19 +0000

Frontiers in Computational Neuroscience. AI-generated image: © kura - stock.adobe.com" data-description="" />It reads. It talks. It collates mountains of data and recommends business decisions. Today’s artificial intelligence might seem more human than ever. However, AI still has several critical shortcomings. ��ϳԹ��Դ (CSHL) NeuroAI Scholar Kyle Daruwalla explains: “As impressive as ChatGPT and all these current AI technologies are, in terms of interacting with...

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Wrexham University awards John Moses Honorary Fellowship

Luis Sandoval — Thu, 13 Jun 2024 11:30:25 +0000

They say you can’t go home again. Try telling that to ��ϳԹ��Դ (CSHL) Professor John Moses. The chemist recently returned to his hometown of Wrexham, a city in the northeast corner of Wales, near the country’s border with England. There, he received a hero’s welcome as he was awarded an Honorary Fellowship...

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Meet Xenopus, the African clawed frog

Luis Sandoval — Thu, 06 Jun 2024 11:30:41 +0000

Xenopus course at CSHL pose with the star of the course, the African clawed frog. Left to right: Rachel Miller, Peter Walentek, Lance Davidson, and Chenbei Chang." data-description="" />Sometimes, groundbreaking biomedical discoveries and technology can come from the strangest sources. A perfect example: Xenopus, the African clawed frog. It swims upside down. It’s see-through. And it makes an ideal test subject for studying genes that may cause or help cure diseases in humans. This year, scientists from around the globe once again descended...

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Nobel laureate honored at CSHL chemistry symposium

Luis Sandoval — Mon, 15 Apr 2024 11:30:48 +0000

Pharmaceutical companies need to make drugs quickly. They need to produce chemical compounds in large amounts. And they need these compounds to have as few harmful side effects as possible. But in reality, many chemical reactions are imperfect and inefficient. Click chemistry is a revolutionary process that allows scientists to cleanly and quickly uncover more...

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Up close and personal with cryo-EM

Luis Sandoval — Thu, 11 Apr 2024 11:30:01 +0000

When it comes to biology, details matter. If a drug isn’t designed to perfectly hit its target, down to a single atom, it may utterly fail. That’s where structural biologists come in. ��ϳԹ��Դ (CSHL) has one of the world’s leading experts. CSHL Professor & HHMI Investigator Leemor Joshua-Tor specializes in the use...

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CSHL goes to the White House for Easter EGGucation

Luis Sandoval — Mon, 08 Apr 2024 11:30:20 +0000

Plant biology and science education are in ��ϳԹ��Դ’s (CSHL’s) DNA. Recently, two CSHL plant scientists brought their expertise from the lab to the White House lawn for an event hosted by First Lady Jill Biden. Since 2022, the White House’s annual “EGGucation” Roll has used fun Easter-themed activities to teach kids about...

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An evolutionary mystery 125 million years in the making

Luis Sandoval — Mon, 04 Mar 2024 19:00:44 +0000

Plant genomics has come a long way since ��ϳԹ��Դ (CSHL) helped sequence the first plant genome. But engineering the perfect crop is still, in many ways, a game of chance. Making the same DNA mutation in two different plants doesn’t always give us the crop traits we want. The question is why...

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Pancreatic cancer lives on mucus

Luis Sandoval — Wed, 28 Feb 2024 12:30:22 +0000

Knowing exactly what’s inside a tumor can maximize our ability to fight cancer. But that knowledge doesn’t come easy. Tumors are clusters of constantly changing cancer cells. Some become common cancer variants. Others morph into deadlier, drug-resistant varieties. No one truly understands what governs this chaotic behavior. Now, ��ϳԹ��Դ (CSHL) Professor David...

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The immune system’s moonlighters

Luis Sandoval — Tue, 20 Feb 2024 12:30:43 +0000

Our immune system is remarkably powerful. It quickly assembles teams of cells to eliminate threats inside our bodies. But sometimes, it hits the wrong target. Autoimmune diseases like lupus and multiple sclerosis result from friendly fire—immune cells attacking healthy tissues and organs by mistake. New treatments and therapeutic targets are direly needed for these conditions....

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Genome sequencing for kids, one LEGO at a time

Luis Sandoval — Tue, 13 Feb 2024 12:30:32 +0000

Remember the first time you snapped two LEGO pieces into place? What about finishing your first LEGO set? Remember that feeling of accomplishment, of everything fitting in its right place? What if you could bring that same sense of satisfaction to science lessons? That’s exactly what ��ϳԹ��Դ’s DNA Learning Center (DNALC) is...

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Luis Sandoval, Author at ���ϳԹ���Դ