Yi Zhong Archives | ��ϳԹ��Դ

Plus-sized fly: a model to understand the mechanisms underlying human obesity

Peter Tarr — Tue, 10 Jan 2017 12:00:06 +0000

Cold Spring Harbor, NY — Why do people become obese? Poor dietary choices and overeating seem like clear causes, but what is at the root of these behaviors? Significantly overweight people may be genetically predisposed to be affected disproportionately when faced with the ready availability of calorie-laden treats. It appears, in others words, that some...

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Study shows how neurons enable us to know smells we like and dislike, whether to approach or retreat

Peter Tarr — Mon, 07 Oct 2013 17:14:18 +0000

Some basic biology learned from study of fruit flies could help us understand food choice in obese people. Cold Spring Harbor, NY — Think of the smell of freshly baking bread. There is something in that smell, without any other cues—visual or tactile—that steers you toward the bakery. On the flip side, there may be a...

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Scientists reverse Alzheimer’s-like memory loss in animal models by blocking EGFR signaling

Communications Department — Mon, 24 Sep 2012 14:26:31 +0000

EGFR inhibitors used to fight cancer show surprising efficacy in fly, mouse models of beta amyloid-associated memory loss Cold Spring Harbor, NY — A team of neuroscientists and chemists from the U.S. and China today publish research suggesting that a class of currently used anti-cancer drugs, as well as several previously untested synthetic compounds, show...

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Alzheimer’s disease: A CSHL study cited as a key advance

Communications Department — Wed, 04 May 2011 15:32:41 +0000

etween November 1, 2004 and December 31, 2010, scientists published tens of thousands of research papers about various aspects of Alzheimer’s disease. In its April issue, Thomson Reuters’ ScienceWatch.com, an open Web resource that has tracked trends and performance in global research since 1989, identified the hottest topics or “research fronts” within the Alzheimer’s field and...

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CSHL neuroscientists reverse Alzheimer’s-like memory loss by targeting signaling protein in fruitflies

Peter Tarr — Mon, 29 Mar 2010 16:40:50 +0000

Cold Spring Harbor, NY — By blocking the cellular signaling activity of a protein, a team of neuroscientists at ��ϳԹ��Դ (CSHL) has prevented memory loss in fruit flies caused by brain plaques similar to those thought to cause Alzheimer’s disease in humans. The study also resolves a long-standing controversy about the role...

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CSHL neuroscientist discovers protein that regulates forgetting of short-term memories

Communications Department — Thu, 18 Feb 2010 14:00:04 +0000

Fruit fly experiments show inhibiting and elevating Rac activity slows and speeds erasure Cold Spring Harbor, NY — Memories that we have just acquired—a new phone number, or the name of a new acquaintance—are more liable to be forgotten than memories we have held for some time. We know this from experience, but we are...

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Scientists demonstrate means of reducing Alzheimer’s-like plaques in fly brain

Communications Department — Mon, 14 Jul 2008 19:00:59 +0000

But overexpression of Neprilysin causes other serious pathologies Cold Spring Harbor, NY — Neuroscientists at ��ϳԹ��Դ (CSHL) are part of a collaboration that has succeeded in demonstrating that overexpression of an enzyme in the brain can reduce telltale deposits causally linked with Alzheimer’s disease. CSHL Professor Yi Zhong, Ph.D., whose lab studies...

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