Raffaella Sordella Archives | ��ϳԹ��Դ

Preventing lung cancer’s unwelcome return

Jasmine Lee — Tue, 13 Jul 2021 12:00:26 +0000

When a doctor gives a patient antibiotics for a bacterial infection, they usually require them to finish the entire treatment, even when symptoms go away. This is to ensure the drugs kill off any remaining bacteria. ��ϳԹ��Դ (CSHL) Visiting Scientist Raffaella Sordella investigated a similar problem that occurs in some lung cancers....

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New research explains why even targeted therapies eventually fail in lung cancer

Peter Tarr — Wed, 29 Mar 2017 12:00:49 +0000

Cold Spring Harbor, NY — Nearly 50 years into the “war” on cancer, doctors possess weapons that once would have seemed magical in their tumor-killing specificity. The drug Tarceva (erlotinib), for example, can virtually erase all traces of aggressive lung cancer tumors in a subset of patients who bear a particular disease-driving mutation in a...

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Researchers identify potentially druggable mutant p53 proteins that promote cancer growth

Peter Tarr — Fri, 09 Dec 2016 08:00:55 +0000

Truncated p53 proteins, presumed unimportant, now point to new drug targets for some of ‘the hardest cancers’ Cold Spring Harbor, NY — Discovered in the 1970s, tumor suppressors are among the most important proteins in the body. A master regulator of growth—“the guardian of the genome”—the p53 protein monitors cell growth for errors. We rely...

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5th Graders spend a day as young scientists

Andrea Alfano — Wed, 16 Dec 2015 18:35:22 +0000

…and it was “the best trip ever.” tiny amoeba crawling across a microscope slide is much more likely to grab kids’ attention than a lecture on single-celled organisms. Any science teacher knows that a hands-on demonstration like setting up a microscope or dissecting an earthworm is the most surefire way to engage kids in learning...

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Swim Across America fundraiser supports lung cancer research at CSHL

Jill Stone — Wed, 12 Aug 2015 20:27:59 +0000

Swim Across America held its annual “Cove to Sound” swim at Morgan’s Park in Glen Cove, NY on August 8, 2015. The event raises important funds to support lung cancer research in Dr. Raffaella Sordella‘s laboratory at CSHL. Nitin Shirole and Paola Pisterzi from Raffaella’s lab participated in the event by swimming and Debjani Pal...

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Cancer metabolism and country music with first-year student Jackie Giovanniello

Communications Department — Mon, 09 Mar 2015 23:24:23 +0000

First-year Watson School student Jackie Giovanniello loves country music. We’ve learned this not so much from Jackie but from her classmates who either now love country music too, or who refuse to ride in her car because of her strict country-only radio policy. Jackie comes from Brooklyn, not an area considered by many to be...

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Experts convene at CSHL to scrutinize, assess low-dose CT screening for lung cancer

Peter Tarr — Fri, 17 Oct 2014 11:49:32 +0000

Cold Spring Harbor, NY — At the first annual Lung Cancer Early Detection and Prevention Workshop held at ��ϳԹ��Դ (CSHL) in late September, nearly two dozen physicians, research scientists and hospital administrators took a close scientific view of rapid advances made in recent years to identify lung cancer at its earliest stages....

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Research may explain how the body’s foremost anti-cancer ‘guardian’ protein learned to switch sides

Peter Tarr — Tue, 29 Jul 2014 14:15:00 +0000

The Sordella lab, in collaboration with the Krainer lab, identified a major new isoform of the tumor suppressor p53, called p53Ψ and showed that it induces expression of markers of the epithelial-mesenchymal transition and enhances the motility and invasive capacity of cells.

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CSHL lung cancer researcher receives $70,000 from Swim Across America-Nassau Suffolk

Communications Department — Mon, 03 Mar 2014 05:00:19 +0000

The Swim Across America (SAA) Nassau Suffolk Committee recently distributed the net proceeds of its 2013 Swims—$500,000—to six Long Island and metro area beneficiaries. Cold Spring Harbor, NY — The Swim Across America (SAA) Nassau Suffolk Committee recently distributed the net proceeds of its 2013 Swims—$500,000—to six Long Island and metro area beneficiaries. The funds...

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Long Island foundation presents check for $15,000 to support CSHL lung cancer research

Communications Department — Tue, 01 Oct 2013 15:50:28 +0000

The Elisabeth R. Woods Foundation (ERWF) presented a check in September for $15,000 to support lung cancer research of CSHL Associate Professor Raffaella Sordella and graduate student Debjani Pal. The Foundation was established in honor of Elisabeth Woods, wife of long time CSHL Association member and current director, James A. Woods. Elisabeth died in 2000...

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Elisabeth R. Woods Foundation marks inaugural year

Communications Department — Tue, 26 Feb 2013 19:48:03 +0000

Local foundation makes an impact in their first year. Cold Spring Harbor, NY — In just their first year, the Elisabeth R. Woods Foundation has raised $27,000 to support lung cancer research in the laboratory of Dr. Raffaella Sordella at ��ϳԹ��Դ (CSHL). The Foundation was established in honor of Elisabeth Woods, wife...

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Elisabeth R. Woods Foundation supports lung cancer research at ��ϳԹ��Դ

Communications Department — Thu, 27 Sep 2012 17:37:29 +0000

The Elisabeth R. Woods Foundation marked its 2012 launch with a $15,000 donation to ��ϳԹ��Դ (CSHL). Cold Spring Harbor, NY — The Elisabeth R. Woods Foundation marked its 2012 launch with a $15,000 donation to ��ϳԹ��Դ (CSHL). The funds will be used for lung cancer research conducted by CSHL Associate...

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CSHL scientist takes the plunge in support of cancer research

Communications Department — Mon, 29 Aug 2011 12:57:47 +0000

he non-profit organization, Swim Across America (SAA), raises funds for cancer research by conducting pool and open water swims across the country. A Long Island-based activity that has gained immense popularity over the last few years is the “Sound to Cove” swim, a ½ mile, 1 mile, 5K, or 10K swim in Long Island Sound...

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One experiment: A cellular battleground in lung cancer

Peter Tarr — Sat, 11 Jun 2011 21:17:19 +0000

Appearances can be deceiving. This image, made by graduate student Matthew Camiolo in the lab of Assistant Professor Raffaella Sordella, seems as captivating as a stained glass window. In fact, it takes us to a cellular battleground the size of a pinhead within a human lung cancer tumor. It’s part of one experiment now underway...

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New mechanisms of tumor resistance to targeted therapy in lung cancer are discovered

Peter Tarr — Wed, 18 Aug 2010 13:25:38 +0000

CSHL-led team demonstrates that increased IL-6 secretion can lead to decreased sensitivity to Tarceva Cold Spring Harbor, NY — One of the most tantalizing developments in anti-cancer therapy over recent years has been the advent of targeted treatments, which have proven highly effective in holding aggressive cancers at bay in certain patients, although typically only...

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CSHL cancer researcher Raffaella Sordella awarded 2010 Damon Runyon-Rachleff Innovation Award

Communications Department — Tue, 19 Jan 2010 13:54:30 +0000

Cold Spring Harbor, NY — Assistant Professor Raffaella Sordella, Ph.D., of ��ϳԹ��Դ (CSHL) has been named one of three recipients of the 2010 Damon Runyon-Rachleff Innovation Awards by the Damon Runyon Cancer Research Foundation. The grant of $450,000 over three years is awarded each year to early-career scientists whose novel approaches have...

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Swim Across America donates $50,000 for cancer research at ��ϳԹ��Դ

Communications Department — Thu, 20 Aug 2009 15:11:03 +0000

Cold Spring Harbor, NY — Swim Across America (SAA) has pledged $50,000 to ��ϳԹ��Դ (CSHL) to support the work of cancer researcher Rafaella Sordella, Ph.D. SAA raised part of the money during its 2009 “Sound to the Cove Swim” held on Saturday, August 15, during which more than 200 swimmers took the...

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Long Island groups raise funds to support local cancer researcher Raffaella Sordella, Ph.D., of ��ϳԹ��Դ

Communications Department — Thu, 23 Apr 2009 15:59:29 +0000

Cold Spring Harbor, NY — Raffaella Sordella, Ph.D., a cancer researcher at ��ϳԹ��Դ (CSHL), has been presented with two checks totaling $10,000 in support of her work. The donations, each in the amount of $5,000, were made by New York State Order Sons of Italy in America (NYSOSIA) and Breast Cancer Help,...

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CSHL scientists trace causal link between a tumor suppressor gene and liver cancer

Communications Department — Mon, 02 Jun 2008 19:07:59 +0000

DLC1 is likely altered in many human cancers and points to new drug targets Cold Spring Harbor, NY — Scientists at ��ϳԹ��Դ (CSHL) have taken the search for cancer-causing genes an important step forward. In a newly published paper, they confirm that a gene called DLC1 is a tumor suppressor. They have...

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��ϳԹ��Դ’s innovative lung cancer research program awarded $100,000 grant

Communications Department — Wed, 09 Jan 2008 19:46:15 +0000

Joan’s Legacy grant will enable CSHL to build upon recent lung cancer discoveries Cold Spring Harbor, NY — ��ϳԹ��Դ’s (CSHL) researcher Raffaella Sordella, Ph.D. was awarded $100,000 by Joan’s Legacy: The Joan Scarangello Foundation to Conquer Lung Cancer. The two-year grant will fund CSHL’s pioneering lung cancer research involving a new class...

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Raffaella Sordella Archives | ���ϳԹ���Դ