neurodegenerative disease Archives | ��ϳԹ��Դ

Fish oil may increase CTE risk after brain injury

Nick Wurm — Tue, 07 Apr 2026 11:30:07 +0000

Neurodegenerative conditions like chronic traumatic encephalopathy (CTE) are often called a silent pandemic. Even so-called “mild” concussions, like those sustained in contact sports, may have a cascading effect over time. CTE symptoms such as mood swings, memory loss, and depression may not appear for decades. A new study suggests one common dietary supplement may, in...

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Researchers find new way to slow memory loss in Alzheimer’s

Gina Dipietro — Thu, 05 Feb 2026 12:30:28 +0000

Alzheimer’s disease is often measured in statistics: millions affected worldwide, cases rising sharply, costs climbing into the trillions. For families, the disease is experienced far more intimately. “It’s a slow bereavement,” says ��ϳԹ��Դ Professor Nicholas Tonks, whose mother lived with Alzheimer’s. “You lose the person piece by piece.” There’s a lot of...

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A doorstop for the brain’s electrical gates

Jennifer Michalowski — Wed, 29 Oct 2025 16:00:04 +0000

Nature, reveals the molecular mechanisms that keep the brain’s NMDA receptors fully or partially open." data-description="Image of NMDA receptors in different positions" />As information zings from cell to cell inside the brain, bursts of electricity spur its transmission. At ��ϳԹ��Դ (CSHL), scientists have turned their attention to the tiny pores that let charged ions enter a cell—and the molecular gatekeepers that help control them. CSHL structural biologist Hiro Furukawa studies NMDA receptors (NMDARs). These...

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Mind-blowing neuroscience research

Communications Department — Tue, 22 Jul 2025 11:30:19 +0000

The brain is the most complex and powerful part of the human body. When things are working as they should, we don’t notice at all. However, any number of conditions can disrupt healthy brain function. ��ϳԹ��Դ (CSHL) neuroscientists focus on understanding how neural connections in the brain translate into behavior. Their research...

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A CSHL Symposium for the ages

Samuel Diamond — Thu, 05 Jun 2025 11:30:05 +0000

You are not the same person you were a decade ago. Most of your body’s cells are replaced every seven to 10 years. Nevertheless, you retain the genes and memories that help make you, you. Science still doesn’t fully understand how the aging process works. But we’re getting closer, and the answers may hold the...

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Cocktails & Chromosomes: Hormones on my mind

Communications Department — Wed, 09 Apr 2025 11:30:14 +0000

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Lucas Cheadle awarded $750K MIND Prize

Samuel Diamond — Tue, 01 Apr 2025 14:00:05 +0000

As the world’s population ages, neurodegenerative conditions like Alzheimer’s disease are becoming more and more common. Alzheimer’s is the leading cause of dementia. And though research into these conditions has yielded many fascinating results, few have translated to clinical applications. Today, we have a better idea of what Alzheimer’s does to the brain. However, we’re...

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Mixed signals: How the brain interprets social cues

Nick Wurm — Mon, 06 Jan 2025 12:30:45 +0000

AI generated voice with Stephen Shea’s actual voice Imagine you’re at a dinner party, but you can’t smell the food cooking or hear the dinner bell. Sounds like a dream, right? What if it wasn’t? “When we experience the world and interact with people, we use all our senses,” ��ϳԹ��Դ Professor Stephen...

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2024 Double Helix Medal recipients Alisa & Daniel Doctoroff

Communications Department — Tue, 03 Dec 2024 12:30:32 +0000

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The Microprocessor inside you

Jennifer Michalowski — Mon, 02 Dec 2024 12:30:49 +0000

It’s a big year for microRNAs. The 2024 Nobel Prize in Physiology or Medicine went to Victor Ambros and Gary Ruvkun, who discovered the first microRNA in 1993. Today, we know that humans make more than 1,000 different microRNAS. These molecules are critical for building and maintaining healthy bodies, so it’s crucial that they’re made...

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19th annual Double Helix Medals dinner raises $7 million

Communications Department — Fri, 15 Nov 2024 21:00:55 +0000

On November 14, ��ϳԹ��Դ (CSHL) held its 19th annual Double Helix Medals dinner (DHMD) at the American Museum of Natural History in New York City. The event, emceed by CBS journalist Lesley Stahl, honored Alisa and Daniel Doctoroff and 2023 Nobel laureate Dr. Katalin Karikó. With the support of the event chairs...

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This protein does “The Twist”

Luis Sandoval — Wed, 31 Jul 2024 15:00:56 +0000

Proteins are constantly performing a kind of dance. They move and contort their bodies to fulfill specific functions inside our bodies. The NMDAR protein executes an especially hard dance routine in our brains. One wrong step can lead to a range of neurological disorders. NMDAR binds to the neurotransmitter, glutamate, and another compound, glycine. These...

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At the Lab Episode 9: Musical mice

Communications Department — Tue, 28 May 2024 11:30:20 +0000

Imagine walking along a busy city sidewalk. How do you know when to change pace with the crowd? Now think about striking up a conversation. How can you tell when to speak faster or slower? CSHL Assistant Professor Arkarup Banerjee seeks to answer these questions with the help of an animal called Alston’s singing mouse.

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Why some RNA drugs work better than others

Jennifer Michalowski — Wed, 06 Mar 2024 12:30:20 +0000

Spinal muscular atrophy, or SMA, is the leading genetic cause of infant death. Less than a decade ago, ��ϳԹ��Դ (CSHL) Professor Adrian Krainer showed this brutal disease can be treated by tweaking a process called RNA splicing. This breakthrough resulted in Spinraza, the first effective treatment for SMA. It also opened a...

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How a mouse’s brain bends time

Luis Sandoval — Tue, 30 Jan 2024 10:00:43 +0000

Life has a challenging tempo. Sometimes, it moves faster or slower than we’d like. Nevertheless, we adapt. We pick up the rhythm of conversations. We keep pace with the crowd walking a city sidewalk. ��ϳԹ��Դ Assistant Professor Arkarup Banerjee explains: “There are many instances where we have to do the same action...

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One Experiment: The brain’s power lines

Nick Wurm — Mon, 22 Jan 2024 12:30:55 +0000

No, that’s not a bird’s-eye view of the Earth at night. Those glowing green lines connecting each dot aren’t highways. And the big dots aren’t cities or towns either. But there are power lines and, in a way, it is still a map. What you’re looking at is a close-up view of neural circuits deep...

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The sound of music … by mice

Communications Department — Fri, 22 Dec 2023 12:30:19 +0000

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Jessica Tollkuhn wins $750K MIND Prize

Nick Wurm — Tue, 25 Apr 2023 14:00:36 +0000

��ϳԹ��Դ Associate Professor Jessica Tollkuhn has won the inaugural Maximizing Innovation in Neuroscience Discovery (MIND) Prize. The $750,000 award will support her research on how sex hormones affect the brain over the course of a lifetime. The Pershing Square Foundation’s MIND Prize honors early-to-mid-career investigators pursuing innovative research on neurodegenerative diseases. “I’m...

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Communication breakdown in the brain

Communications Department — Tue, 03 Jan 2023 12:30:21 +0000

Seizures come suddenly, triggered by stress, fever, flashing lights, or even just feeling tired. Some cause the body to jerk and shake while others can produce strange sensations, make one lose a sense of awareness, or faint. They can happen when the person is awake or asleep. When they pass, after a few seconds or...

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CSHL breaks ground on new Neuroscience Research Complex

Samuel Diamond — Tue, 20 Dec 2022 22:00:09 +0000

Shovels pierced soil, declaring the dawn of a new era at ��ϳԹ��Դ (CSHL). On December 19, 2022, CSHL faculty and staff joined with state and local leaders for a groundbreaking ceremony at the Laboratory’s headquarters in Cold Spring Harbor, New York. Among those present was the state’s second-highest-ranking official, Lieutenant Governor Antonio...

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neurodegenerative disease Archives | ���ϳԹ���Դ