Michael Schatz Archives | ��ϳԹ��Դ

The world’s first DNA “tricorder” in your pocket

Luis Sandoval — Mon, 07 Dec 2020 08:00:48 +0000

��ϳԹ��Դ (CSHL) scientists developed the world’s first mobile genome sequence analyzer, a new iPhone app called iGenomics. By pairing an iPhone with a handheld DNA sequencer, users can create a mobile genetics laboratory, reminiscent of the “tricorder” featured in Star Trek. The iGenomics app runs entirely on the iOS device, reducing the...

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The DNA tricks that gave us 100 different kinds of tomatoes

Jennifer Michalowski — Wed, 17 Jun 2020 15:00:32 +0000

An expansive new analysis of genetic variation among tomatoes has uncovered 230,000 previously hidden large-scale differences in DNA between varieties. As tomato plants evolved, segments of DNA were deleted, duplicated, or rearranged. These genomic “structural variations” underpin the vast diversity among tomatoes, changing flavors, altering yield, and shaping other important traits. The study, a collaborative...

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CSHL investigators rank among world’s most highly cited

Brian Stallard — Wed, 11 Dec 2019 14:00:14 +0000

Seven researchers affiliated with ��ϳԹ��Դ (CSHL) have been named among the scientists producing the top 1 percent of the most highly cited research in the world. They join CSHL Professor Michael Wigler, who is listed as one of the most extensively cited researchers of all time. The annual Highly Cited Researchers list...

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Watson School alumni spotlights

Communications Department — Sun, 19 May 2019 21:30:53 +0000

This year, the Watson School of Biological Sciences celebrates the 20th anniversary of its first entering class of six Ph.D. candidates in September 1999. At CSHL, students are introduced to a broad and multi-disciplinary way to study biological sciences, and think critically to solve problems in their research. The school’s mission has remained the same...

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Massive genome havoc in breast cancer is revealed

Peter Tarr — Fri, 13 Jul 2018 01:20:22 +0000

Cold Spring Harbor, NY — In cancer cells, genetic errors wreak havoc. Misspelled genes, as well as structural variations—larger-scale rearrangements of DNA that can encompass large chunks of chromosomes—disturb carefully balanced mechanisms that have evolved to regulate cell growth. Genes that are normally silent are massively activated and mutant proteins are formed. These and other...

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New method can more precisely determine when a cell has ‘cashed’ RNA ‘checks’ written by active genes

Peter Tarr — Fri, 26 Jan 2018 21:15:47 +0000

Cold Spring Harbor, NY — DNA has often been called “the book of life,” but this popular phrase makes some biologists squirm a bit. True, DNA bears our genes, which spell out the instructions our cells use to make proteins—those workhorse molecules that make just about everything in life possible. But the precise relationship between...

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Scientists sequence genome of worm that can regrow body parts, seek stem cell insights

Communications Department — Mon, 21 Sep 2015 15:00:08 +0000

M. lignano and diagrammatic key. The tiny worm intrigues scientists because it can regenerate almost its whole body following an injury. Hence, their effort to sequence its genome." data-description="" />Worm’s genome could lead to better understanding of its regenerative prowess and advance stem cell biology Cold Spring Harbor, NY — Tourists spending a recuperative holiday on the Italian coast may be envious of the regenerative abilities of locally found flatworm Macrostomum lignano. Named for its discovery near the Italian beach town of Lignano Sabbiadoro,...

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Mathematical ‘Gingko trees’ reveal mutations in single cells that characterize diseases

Communications Department — Fri, 04 Sep 2015 19:58:10 +0000

The Schatz lab, in collaboration with the Wigler and Atwal labs, has developed a new interactive, open-source analysis program called Gingko that can be used to reduce the uncertainty of single-cell analysis and visualize patterns in copy number mutations across populations of cells.

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The biggest beast in the Big Data forest? One field’s astonishing growth is, well, ‘genomical’!

Peter Tarr — Mon, 06 Jul 2015 15:40:03 +0000

Cold Spring Harbor, NY — Who’s about to become the biggest beast in the Big Data forest? A group of math and computing experts have arrived at what they say is a clear answer. It’s not YouTube or Twitter, social media sites that gobble up awesome quantities of bandwidth and generate hard-to-grasp numbers of electronic...

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Third-year student Tyler Garvin brings together engineering and medicine to help save lives

Communications Department — Mon, 22 Jun 2015 17:31:05 +0000

In the human body, it is neatly tucked between the stomach and spine, surrounded by other vital organs on all sides. Named by ancient Greek scientist Ruphos, its moniker, meaning “all flesh,” gives a decent description of what it looks like but not necessarily what it does: about six inches in length and shaped like...

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A unique partnership

Communications Department — Tue, 24 Mar 2015 15:46:07 +0000

This post was written by Skyler Palatnick, a junior at Cold Spring Harbor High School with a penchant for writing about scientists. His first contribution to LabDish was about CSHL Director of Research David L. Spector. In this post, he introduces us to someone closer to home. 14-year-old with an internship? Not very common. A...

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CSHL quantitative biologist Michael Schatz awarded 2015 Sloan Foundation Research Fellowship

Peter Tarr — Fri, 20 Feb 2015 15:40:17 +0000

Cold Spring Harbor, NY — Associate Professor Michael Schatz of ��ϳԹ��Դ (CSHL) will receive a 2015 Alfred P. Sloan Foundation Research Fellowship. This prestigious research award has been issued since 1955. Schatz is one of 126 outstanding early-career scientists from the U.S. and Canada recognized by the Foundation this year. Past honorees...

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New study casts sharpest light yet on genetic mysteries of autism

Peter Tarr — Wed, 29 Oct 2014 14:00:32 +0000

Our picture of how genetic errors contribute to autism has just gotten sharper. Cold Spring Harbor, NY — Our picture of how genetic errors contribute to autism has just gotten sharper. The latest series of clarifications in what, in its totality, is a very complex puzzle, emerges from new research published in Nature today by...

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A shift in the code: New method reveals hidden genetic landscape

Communications Department — Mon, 18 Aug 2014 14:33:24 +0000

Scientists develop algorithm to uncover genomic insertions and deletions involved in autism, OCD Cold Spring Harbor, NY — With three billion letters in the human genome, it seems hard to believe that adding a DNA base here or removing a DNA base there could have much of an effect on our health. In fact, such...

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CSHL quantitative biologist Michael Schatz wins prestigious NSF Early CAREER Award

Peter Tarr — Tue, 29 Jul 2014 14:30:55 +0000

The National Science Foundation (NSF) has selected Assistant Professor Michael Schatz, Ph.D., of ��ϳԹ��Դ (CSHL) to receive its prestigious CAREER Award. Cold Spring Harbor, NY — The National Science Foundation (NSF) has selected Assistant Professor Michael Schatz, Ph.D., of ��ϳԹ��Դ (CSHL) to receive its prestigious CAREER Award. The Faculty...

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Seedlings for science

Public Affairs Administrator — Thu, 24 Jul 2014 20:43:37 +0000

CSHL scientists connect with kids. Outreach activities by CSHL scientists are made possible through grants and donations from public and private sources, including the National Science Foundation.

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“When I grow up…”

Communications Department — Thu, 24 Jul 2014 19:51:44 +0000

rowing up, I always knew I wanted to work in science. Maybe I’d synthesize a new biodegradable plastic. Or maybe I’d unlock the secrets behind Alzheimer’s disease. Maybe I’d teach science at a university or write about amazing discoveries. Kids often dream of pursuing unlikely professions, like acting in Hollywood or playing major league baseball....

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CSHL receives $50 million to establish Simons Center for Quantitative Biology

Dagnia Zeidlickis — Mon, 07 Jul 2014 06:28:00 +0000

��ϳԹ��Դ (CSHL) today announced a $50 million gift from Jim and Marilyn Simons to establish the Simons Center for Quantitative Biology. Cold Spring Harbor, NY — ��ϳԹ��Դ (CSHL) today announced a $50 million gift from Jim and Marilyn Simons to establish the Simons Center for Quantitative Biology. The Center...

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How biological data science can improve our health, food & energy

Public Affairs Administrator — Fri, 27 Jun 2014 20:40:08 +0000

Given by Assistant Professor Michael Schatz, Ph.D. We are in the middle of an incredible transition in biology, driven by the rapidly improved throughput and falling costs of DNA sequencing. These technologies are used, among many other applications, for studying the genetic components of Cancer, Autism and other complex diseases, and to probe the natural...

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Putting together the genome with first-year student Maria Nattestad

Communications Department — Thu, 22 May 2014 02:10:42 +0000

In 1990, the effort to sequence the human genome began, led, in part, by ��ϳԹ��Դ’s then-director Jim Watson. Scientists anticipated the project would reveal about 100,000 genes occupying the 3.3 billion bases of DNA. The human genome sequence would help us understand and treat thousands of diseases with genetic contributions. Sequencing cost between $2 and...

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Michael Schatz Archives | ���ϳԹ���Դ