lung cancer Archives | ��ϳԹ��Դ

Shapeshifting cancers’ masters, unmasked

Jen A. Miller — Mon, 24 Nov 2025 12:30:01 +0000

Some tumors are almost impossible to treat. That’s especially true for carcinomas, which don’t behave like other malignancies. Some of these tumors act as shapeshifters and start to resemble cells from other organs of the human body, such as skin. This bizarre behavior presents a challenge for existing therapies. “The tumors are notoriously plastic in...

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Flipping cancer’s off switch

Communications Department — Thu, 07 Nov 2024 12:30:54 +0000

If there’s one thing cancer knows, it’s growth. Over the last two decades, scientists have observed that many cancers progress by activating a set of proteins called YAP and TAZ, which control cell growth and organ size. When left uncontrolled, YAP/TAZ can lead to tumor formation. So, if you’re looking for new drug targets, why...

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At the Lab Episode 18: The stress of cancer

Communications Department — Tue, 06 Aug 2024 11:30:42 +0000

In this week’s edition of At the Lab, we sit down with CSHL Adjunct Professor Mikala Egeblad to discuss one of our latest breakthroughs in cancer research. It’s a sobering conversation that should hit close to home for anyone who’s ever been diagnosed with cancer, as well as all of us who have lost loved...

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Chronic stress spreads cancer … here’s how

Margaret Osborne — Thu, 22 Feb 2024 16:00:10 +0000

Stress is inevitable. But too much of it can be terrible for our health. Chronic stress can increase our risk for heart disease and strokes. It may also help cancer spread. How this works has remained a mystery—a challenge for cancer care. Xue-Yan He, a former postdoc in ��ϳԹ��Դ (CSHL) Adjunct Professor...

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In cancer immunotherapy, more isn’t necessarily better

Margaret Osborne — Thu, 14 Sep 2023 15:00:50 +0000

DNA mismatch repair deficiency (MMRd) is a genetic condition often associated with colon cancer. It can happen in otherwise normal cells before cancer forms or after a tumor has already formed. The condition makes it hard for cells to correct mistakes that occur in DNA copying. This can lead to many mutations within tumors, or...

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Getting tough on tuft cell lung cancer

Jennifer Michalowski — Wed, 22 Jun 2022 11:30:56 +0000

��ϳԹ��Դ (CSHL) Professor Christopher Vakoc’s team discovered in 2018 a new type of small-cell lung cancer. The cancer originates from cells known as tuft cells. The prognosis for tuft cell lung cancer is extremely poor. Now, the Vakoc team has discovered how tuft cells are generated in the body. Disrupting tuft cell...

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Preventing lung cancer’s unwelcome return

Jasmine Lee — Tue, 13 Jul 2021 12:00:26 +0000

When a doctor gives a patient antibiotics for a bacterial infection, they usually require them to finish the entire treatment, even when symptoms go away. This is to ensure the drugs kill off any remaining bacteria. ��ϳԹ��Դ (CSHL) Visiting Scientist Raffaella Sordella investigated a similar problem that occurs in some lung cancers....

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How a sleeping cancer awakens and metastasizes

Peter Tarr — Thu, 27 Sep 2018 18:00:29 +0000

Cold Spring Harbor, NY — Scientists at ��ϳԹ��Դ (CSHL) have determined one of the ways in which cancers in remission can spring back into action. This knowledge has inspired a new treatment idea designed to prevent cancer recurrence and metastasis. Even after successful cancer treatment, dormant, non-dividing cancer cells that previously detached...

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Elisabeth R. Woods Foundation donates to cancer research

Jill Stone — Tue, 17 Jul 2018 13:17:29 +0000

On June 10th, ��ϳԹ��Դ (CSHL) welcomed donors of the Elisabeth R. Woods Foundation to a special gathering in support of lung cancer research. Elisabeth Woods’ granddaughter, Mary Leonard, welcomed the distinguished guests, and in her opening remarks, told the story of her grandmother’s battle with non-small cell lung cancer and the Elisabeth...

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Researchers discover new type of lung cancer

Communications Department — Thu, 28 Jun 2018 15:17:27 +0000

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Researchers discover new type of lung cancer

Communications Department — Mon, 25 Jun 2018 21:01:12 +0000

Cold Spring Harbor, NY — Researchers have discovered a new kind of small-cell lung cancer (SCLC). The discovery paves the way for developing personalized medicine approaches to target this previously unnoticed form of the disease. “Cancer is not one thing, it’s actually hundreds of distinct diseases.” This common refrain helps explain the frustrating experience oncologists...

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Three Strohm Sisters Family Foundation donates $5,000 for research on lung cancer recurrence

Jill Stone — Mon, 08 Jan 2018 23:44:31 +0000

On December 18, 2017, Ed Strohm of the Three Strohm Sisters Family Foundation presented CSHL Associate Professor Mikala Egeblad with a check for $5,000 to support her ongoing lung cancer research. This is the first donation ��ϳԹ��Դ has received from the Long Island-based foundation, which is dedicated to the eradication of cancer....

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Next-gen cancer test

Peter Tarr — Fri, 24 Nov 2017 17:00:40 +0000

Knowing that cancers become lethal when they spread, investigators at ��ϳԹ��Դ (CSHL) seek a way of detecting tumors much earlier than now possible—when they’re more likely to be curable. Fleshing out an idea Professor Michael Wigler had years ago—before there was technology to act on it—research led by Associate Professor Alexander Krasnitz...

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CSHL to lead international team developing next-generation organoid cancer research

Peter Tarr — Thu, 11 May 2017 09:00:26 +0000

��ϳԹ��Դ (CSHL) has been awarded a research subcontract by Leidos Biomedical Research to lead a Cancer Model Development Center

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New research explains why even targeted therapies eventually fail in lung cancer

Peter Tarr — Wed, 29 Mar 2017 12:00:49 +0000

Cold Spring Harbor, NY — Nearly 50 years into the “war” on cancer, doctors possess weapons that once would have seemed magical in their tumor-killing specificity. The drug Tarceva (erlotinib), for example, can virtually erase all traces of aggressive lung cancer tumors in a subset of patients who bear a particular disease-driving mutation in a...

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Experts convene at CSHL to scrutinize, assess low-dose CT screening for lung cancer

Peter Tarr — Fri, 17 Oct 2014 11:49:32 +0000

Cold Spring Harbor, NY — At the first annual Lung Cancer Early Detection and Prevention Workshop held at ��ϳԹ��Դ (CSHL) in late September, nearly two dozen physicians, research scientists and hospital administrators took a close scientific view of rapid advances made in recent years to identify lung cancer at its earliest stages....

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Long Island foundation presents check for $15,000 to support CSHL lung cancer research

Communications Department — Tue, 01 Oct 2013 15:50:28 +0000

The Elisabeth R. Woods Foundation (ERWF) presented a check in September for $15,000 to support lung cancer research of CSHL Associate Professor Raffaella Sordella and graduate student Debjani Pal. The Foundation was established in honor of Elisabeth Woods, wife of long time CSHL Association member and current director, James A. Woods. Elisabeth died in 2000...

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Elisabeth R. Woods Foundation marks inaugural year

Communications Department — Tue, 26 Feb 2013 19:48:03 +0000

Local foundation makes an impact in their first year. Cold Spring Harbor, NY — In just their first year, the Elisabeth R. Woods Foundation has raised $27,000 to support lung cancer research in the laboratory of Dr. Raffaella Sordella at ��ϳԹ��Դ (CSHL). The Foundation was established in honor of Elisabeth Woods, wife...

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Elisabeth R. Woods Foundation supports lung cancer research at ��ϳԹ��Դ

Communications Department — Thu, 27 Sep 2012 17:37:29 +0000

The Elisabeth R. Woods Foundation marked its 2012 launch with a $15,000 donation to ��ϳԹ��Դ (CSHL). Cold Spring Harbor, NY — The Elisabeth R. Woods Foundation marked its 2012 launch with a $15,000 donation to ��ϳԹ��Դ (CSHL). The funds will be used for lung cancer research conducted by CSHL Associate...

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Splicing studies detail a protein’s role in creating cancer’s mixed messages

Communications Department — Mon, 13 Feb 2012 18:55:33 +0000

ancer cells are a hotbed of mixed or incorrect molecular “messages”—a result of defects in a cellular mechanism called RNA splicing. When a cell’s DNA is copied into an intermediary molecule called RNA, splicing is the editing step that removes unwanted bits of the RNA message while pasting the rest, called exons, together. The edited...

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lung cancer Archives | ���ϳԹ���Դ

Shapeshifting cancers’ masters, unmasked

Flipping cancer’s off switch

At the Lab Episode 18: The stress of cancer

Chronic stress spreads cancer … here’s how

In cancer immunotherapy, more isn’t necessarily better

Getting tough on tuft cell lung cancer

Preventing lung cancer’s unwelcome return

How a sleeping cancer awakens and metastasizes

Elisabeth R. Woods Foundation donates to cancer research

Researchers discover new type of lung cancer

Researchers discover new type of lung cancer

Three Strohm Sisters Family Foundation donates $5,000 for research on lung cancer recurrence

Next-gen cancer test

CSHL to lead international team developing next-generation organoid cancer research

New research explains why even targeted therapies eventually fail in lung cancer

Experts convene at CSHL to scrutinize, assess low-dose CT screening for lung cancer

Long Island foundation presents check for $15,000 to support CSHL lung cancer research

Elisabeth R. Woods Foundation marks inaugural year

Elisabeth R. Woods Foundation supports lung cancer research at ���ϳԹ���Դ

Splicing studies detail a protein’s role in creating cancer’s mixed messages

lung cancer Archives | ��ϳԹ��Դ

Elisabeth R. Woods Foundation supports lung cancer research at ��ϳԹ��Դ