Ivan Iossifov Archives | ��ϳԹ��Դ

Empowering Insights: The science behind health

Communications Department — Mon, 18 Nov 2024 12:30:22 +0000

The opportunity to turn curiosity into discoveries that impact the human condition is at the core of ��ϳԹ��Դ’s mission. Our scientists are empowered to ask big questions and search for solutions to biology’s most challenging problems. Doing that requires interdisciplinary study, and the Laboratory’s brain-body physiology program encourages our scientists to confront...

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At the Lab Season 1 Research Rewind: Genetics

Communications Department — Tue, 22 Oct 2024 11:30:28 +0000

Much of what makes humans human is also found across all animal and plant life. In other words, genetics is everywhere you look. That’s especially true here At the Lab. This week’s Research Rewind features scientists from all across CSHL, including Christopher Hammell, Ivan Iossifov, Tobias Janowitz, Zachary Lippman, and Rob Martienssen. We also check...

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Autism genetics: The faces behind the data

Margaret Osborne — Thu, 16 May 2024 11:30:35 +0000

More than 5.4 million adults in the U.S. have autism. That’s about the populations of Los Angeles and Phoenix combined. Autism, or autism spectrum disorder (ASD), is a developmental disability that affects how a person experiences the world around them. If this definition sounds broad, there’s a reason for that. Autism manifests in many different...

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President’s essay: Bringing bold visions to life

Communications Department — Fri, 26 May 2023 11:30:08 +0000

The art of high-impact research, which is at the core of ��ϳԹ��Դ (CSHL), is to pursue important questions, follow unanticipated leads, and be bold in crafting new ideas. In this way, we challenge our researchers to move science into new frontiers. While our scientists have freedom to pursue their ideas, they are...

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The evolution of autism research

Luis Sandoval — Thu, 25 May 2023 11:30:32 +0000

The scientific community’s views on autism spectrum disorder (ASD) have changed significantly over the last two decades. ��ϳԹ��Դ (CSHL) has played an important role in this evolution, as our scientists have uncovered several genetic factors underlying ASD. Of course, that evolution didn’t happen overnight. It is the result of progressive research that...

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Autism in the family tree

Communications Department — Tue, 23 May 2023 11:30:47 +0000

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Siblings with autism share more of dad’s genome, not mom’s

Luis Sandoval — Mon, 22 May 2023 11:30:51 +0000

��ϳԹ��Դ (CSHL) researchers have flipped the script on autism spectrum disorder (ASD) genetics. Scientists long thought that siblings born with ASD share more of their mother’s genome than their father’s. But CSHL Associate Professor Ivan Iossifov and Professor Michael Wigler have now shown that, in many cases, it’s dad who might be...

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How well do you know autism spectrum disorders?

Nick Fiore — Mon, 24 Apr 2023 11:30:32 +0000

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Portrait of a Neuroscience Powerhouse

Peter Tarr — Fri, 27 Apr 2018 16:07:30 +0000

At noon every Tuesday from September through June, scenes from a revolution in neuroscience are playing out at ��ϳԹ��Դ. Week after week, over 100 scientists cram themselves into a ground-floor meeting room in the Beckman Laboratory. It’s standing-room only as everyone in the Neuroscience Program settles in to hear details of the...

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Autism genetics study calls attention to impaired motor skills, general cognitive impairment

Peter Tarr — Wed, 07 Feb 2018 19:14:06 +0000

Cold Spring Harbor, NY — A new study of the genetic factors involved in the causation of autism spectrum disorders (ASD) draws fresh attention to the impact these illnesses have on motor skills, and more broadly on cognitive function. “Diminished motor skills appear to be an almost universal property of children with autism,” says Professor...

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Why is autism more common in boys?

Andrea Alfano — Fri, 29 Apr 2016 15:48:55 +0000

Boys diagnosed with autism far outnumber their female counterparts. Autism genetics researcher Ivan Iossifov lays out what research into the disorder’s genetic basis reveals about the reasons for this striking pattern. any of the numbers pegged to autism are staggering. By some estimates, as many as 1 in 68 children lies somewhere along the autism...

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What do autism “risk genes” do?

Andrea Alfano — Thu, 21 Apr 2016 14:16:32 +0000

Autism’s genetic roots are notoriously tricky to untangle, but researchers are beginning to understand how particular genes may contribute to the disorder. Among those researchers is CSHL’s Ivan Iossifov. or some disorders, genetics explains everything. Hemophilia is a good example: the abnormally profuse bleeding associated with it is neatly accounted for by a defect in...

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How many autism “risk genes” have scientists found?

Andrea Alfano — Thu, 14 Apr 2016 14:18:38 +0000

Autism genetics researchers are building up a list of autism “risk genes” by looking into the genomes of families affected by the disorder. CSHL’s Ivan Iossifov is one of the researchers leading the charge. utism is now widely thought of as a spectrum of related disorders, and it is becoming clear that its genetic roots...

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Where does autism come from when it doesn’t run in the family?

Andrea Alfano — Thu, 07 Apr 2016 20:49:42 +0000

Autism genetics expert Ivan Iossifov breaks down recent research that sheds light on how unaffected parents can pass autism onto their child. arents with no history of autism in their families have a child who is diagnosed with the disorder. It’s a common and upsetting story. A quick Google search for “autism causes” is all it...

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Genetic analysis supports prediction that spontaneous rare mutations cause half of autism

Peter Tarr — Tue, 22 Sep 2015 12:57:05 +0000

Quantitative study identifies 239 genes whose “vulnerability” to devastating de novo mutation makes them priority research targets Cold Spring Harbor, NY — A team led by researchers at ��ϳԹ��Դ (CSHL) this week publishes in PNAS a new analysis of data on the genetics of autism spectrum disorder (ASD). One commonly held theory...

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New study casts sharpest light yet on genetic mysteries of autism

Peter Tarr — Wed, 29 Oct 2014 14:00:32 +0000

Our picture of how genetic errors contribute to autism has just gotten sharper. Cold Spring Harbor, NY — Our picture of how genetic errors contribute to autism has just gotten sharper. The latest series of clarifications in what, in its totality, is a very complex puzzle, emerges from new research published in Nature today by...

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A shift in the code: New method reveals hidden genetic landscape

Communications Department — Mon, 18 Aug 2014 14:33:24 +0000

Scientists develop algorithm to uncover genomic insertions and deletions involved in autism, OCD Cold Spring Harbor, NY — With three billion letters in the human genome, it seems hard to believe that adding a DNA base here or removing a DNA base there could have much of an effect on our health. In fact, such...

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CSHL receives $50 million to establish Simons Center for Quantitative Biology

Dagnia Zeidlickis — Mon, 07 Jul 2014 06:28:00 +0000

��ϳԹ��Դ (CSHL) today announced a $50 million gift from Jim and Marilyn Simons to establish the Simons Center for Quantitative Biology. Cold Spring Harbor, NY — ��ϳԹ��Դ (CSHL) today announced a $50 million gift from Jim and Marilyn Simons to establish the Simons Center for Quantitative Biology. The Center...

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A striking link is found between the Fragile-X gene and mutations that cause autism

Peter Tarr — Wed, 25 Apr 2012 14:01:23 +0000

Cold Spring Harbor, NY — A team led by scientists at ��ϳԹ��Դ (CSHL) publishes research today indicating a striking association between genes found disrupted in children with autism and genes that are targets of FMRP, the protein generated by the gene FMR1, whose dysfunction causes Fragile-X syndrome. The new study appears online...

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Ivan Iossifov Archives | ���ϳԹ���Դ