Grigori Enikolopov Archives | ��ϳԹ��Դ

Neurobiologists find chronic stress in early life causes anxiety, aggression in adulthood

Peter Tarr — Thu, 27 Mar 2014 01:00:51 +0000

Cold Spring Harbor, NY — In recent years, behavioral neuroscientists have debated the meaning and significance of a plethora of independently conducted experiments seeking to establish the impact of chronic, early-life stress upon behavior—both at the time that stress is experienced, and upon the same individuals later in life, during adulthood. These experiments, typically conducted...

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Scientists uncover source of ovarian stem-like cells prone to give rise to ovarian cancer

Communications Department — Wed, 06 Mar 2013 18:06:00 +0000

Cold Spring Harbor, NY — In collaboration with colleagues at Cornell University, a team of cancer researchers at ��ϳԹ��Դ (CSHL) has discovered cells with stem-cell properties in the ovary that can mutate to form tumors. The team demonstrated that when two important tumor suppressor genes are inactivated, a previously unknown subset of...

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Study identifies stem cell-related changes that may contribute to age-related cognitive decline

Communications Department — Thu, 05 May 2011 16:49:57 +0000

Age-related drop in new neurons may be due to “single use” or “disposable” nature of adult stem cells in the brain Cold Spring Harbor, NY — A new study from ��ϳԹ��Դ (CSHL) offers an explanation for why our brains produce fewer and fewer neurons with age, a phenomenon thought to underlie age-related...

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CSHL scientists identify elusive neuronal targets of deep brain stimulation

Communications Department — Wed, 15 Dec 2010 18:29:51 +0000

Study might provide new clues to designing better treatments for depression and other neuropsychiatric disorders Cold Spring Harbor, NY — Shooting steady pulses of electricity through slender electrodes into a brain area that controls complex behaviors has proven to be effective against several therapeutically stubborn neurological and neuropsychiatric disorders. Now, a new study has found...

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One experiment: Watching deep brain stimulation spur neuronal birth

Communications Department — Wed, 15 Dec 2010 15:20:51 +0000

Deep brain stimulation (DBS)—which involves shooting steady pulses of electricity through slender, implanted electrodes—acts like a pacemaker in the brain. It greatly reduces the tremors, stiffness and movement problems that are characteristic of Parkinson’s disease, and works against other brain disorders such as epilepsy and severe depression, as well. CSHL’s Dr. Grigori Enikolopov recently teamed...

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Researchers discover that one type of stem cell creates a niche for another type within bone marrow

Communications Department — Thu, 12 Aug 2010 18:03:18 +0000

Understanding how blood stem cells are maintained within the niche offers new opportunities to exploit them therapeutically Cold Spring Harbor, NY — Hematopoietic stem cells (HSCs) have two unique abilities that are prized by medical researchers: to self-renew and to develop into any kind of blood cell, which enables them to replenish the entire blood...

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Scientists find stem cells for the first time in the pituitary

Communications Department — Mon, 28 Apr 2008 19:23:15 +0000

in vitro." data-description="" />Their presence in the hormone-secreting gland of mice suggests a means of adapting to stress and life changes Cold Spring Harbor, NY — A team of researchers led by scientists at ��ϳԹ��Դ have for the first time identified stem cells that allow the pituitary glands of mice to grow even after birth....

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Brain stem cells sensitive to space radiation

Communications Department — Wed, 12 Dec 2007 01:11:37 +0000

Cold Spring Harbor, NY — ��ϳԹ��Դ (CSHL) scientists recently led a team of researchers to study potential effects of space radiation on astronauts. The results of their study are revealing and will provide the foundation for ensuring the safety of crew members participating in long distance space travel. Measures to protect astronauts...

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Team of scientists develops non-invasive method to track nerve-cell development in live human brain

Communications Department — Thu, 08 Nov 2007 05:00:00 +0000

Diagnostic Applications Foreseen in Cancer, Neurological and Psychiatric Illnesses Cold Spring Harbor, NY — A team of scientists including researchers at ��ϳԹ��Դ (CSHL) have identified and validated the first biomarker that permits neural stem and progenitor cells (NPCs) to be tracked, non-invasively, in the brains of living human subjects. This important advance...

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Prozac’s target revealed

Communications Department — Mon, 15 May 2006 20:39:19 +0000

Researchers at ��ϳԹ��Դ on Long Island have identified which among several different kinds of cells in the brain is the chief target of the widely prescribed antidepressant Prozac. This discovery might enable a new generation of more specific treatments for depression, with fewer side effects, to be developed. The findings also lay the foundation for many...

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Father Tom funds Parkinson’s research at ��ϳԹ��Դ

Communications Department — Mon, 09 May 2005 19:13:57 +0000

In October 2004, The Thomas Hartman Foundation for Parkinson’s Research pledged $4.4 million over five years to create the new Thomas Hartman Parkinson’s Research Laboratory at ��ϳԹ��Դ to focus on three core areas of Parkinson’s research: genes, cells and circuits. Dr. Jonathan Sebat and Dr. Nick Tonks will focus on identifying novel...

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Cold Spring Harbor researchers awarded $200,000 in research grants

Communications Department — Thu, 23 Sep 2004 05:00:00 +0000

The National Alliance for Research on Schizophrenia and Depression (NARSAD) awarded $100,000 Independent Investigator grants to Grigori Enikolopov, Ph.D., and Zachary Mainen, Ph.D., both of ��ϳԹ��Դ. The awards were announced in July, with funding starting September 15, 2004. Dr. Enikolopov’s neural stem cell research should further understanding of the neural basis for...

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Nitric oxide regulates stem cell division in the adult brain

Communications Department — Mon, 28 Jul 2003 05:00:00 +0000

Strategy Seen for Repairing Brain Damage Caused by Neurodegenerative Disease and Stroke Cold Spring Harbor, NY — Most neurons in the mammalian brain are produced during embryonic development. However, several regions of the adult brain continue to spawn large numbers of neurons through the proliferation of neural stem cells. Moreover, it is becoming clear that...

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Scientists reveal role for nitric oxide during brain development

Communications Department — Wed, 14 Nov 2001 05:00:00 +0000

Scientists at ��ϳԹ��Դ have found that experimentally altering nitric oxide levels in the developing brain of tadpoles significantly affects brain size and the number of brain cells. The study is significant because it is the first definitive demonstration of the essential role of nitric oxide during vertebrate brain development. Grigori Enikolopov, the...

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Grigori Enikolopov Archives | ���ϳԹ���Դ