anxiety Archives | ��ϳԹ��Դ

Deciphering brain diseases with click chemistry

Communications Department — Tue, 18 Feb 2025 12:30:53 +0000

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Ketamine: From club drug to antidepressant?

Samuel Diamond — Fri, 14 Feb 2025 16:00:46 +0000

AI generated voice Ketamine has received a Hollywood makeover. It used to be known as a rave drug (street name special K) and cat anesthetic. However, in recent years, some doctors have prescribed ketamine to treat conditions from post-traumatic stress disorder to depression. “The practice is not without controversy,” notes ��ϳԹ��Դ (CSHL)...

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Danger or pleasure? How we learn to tell the difference

Margaret Osborne — Wed, 05 Apr 2023 15:00:22 +0000

Deep within our brain’s temporal lobes, two almond-shaped cell masses help keep us alive. This tiny region, called the amygdala, assists with a variety of brain activities. It helps us learn and remember. It triggers our fight-or-flight response. It even promotes the release of a feel-good chemical called dopamine. Scientists have learned all this by...

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Mom’s protective behaviors run deep

Communications Department — Thu, 24 Mar 2022 15:00:53 +0000

The image of a mouse mom fetching her pup safely home calls to mind a human mother’s rapid response when their toddler wanders toward danger. Neuroscientists at ��ϳԹ��Դ (CSHL) now report this resemblance applies in more ways than one. In a first-of-its-kind study, postdoctoral fellow Roman Dvorkin and CSHL Associate Professor Stephen...

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How the brain balances pleasure and pain

Jennifer Michalowski — Tue, 31 Dec 2019 16:00:47 +0000

As our brains take in information about the world and use it to steer our actions, two key principles guide our choices: seek pleasure and avoid pain. Researchers at ��ϳԹ��Դ (CSHL) have zeroed in on an information-processing hub in the brains of mice to discover how neurons there divide the labor to...

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Interview with a neuroscientist

Charlotte Hu — Fri, 31 May 2019 13:18:26 +0000

Comprised of a M.C. Escher-esque network of pathways, the brain is a maze of chaotic proportions. In its full-functioning glory, the brain helps us move, think, dream, and create. It’s a beautiful marvel of evolution that coordinates and translates messages from cells into emotions, memories, and actions. But what happens in the brain when its...

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Brain, interrupted

Charlotte Hu — Fri, 31 May 2019 13:09:13 +0000

{“questions”:{“nk5k0”:{“id”:”nk5k0″,”mediaType”:”image”,”answerType”:”text”,”imageCredit”:”Edvard Munch ‘The Scream'”,”image”:”https:\/\/www.cshl.edu\/wp-content\/uploads\/2019\/05\/The_Scream-Edvard-Munch.jpg”,”imageId”:”28655″,”video”:””,”imagePlaceholder”:””,”imagePlaceholderId”:””,”title”:”In a normal brain, we have a programmed response to a threatening situation. In a brain riddled with anxiety, that normal program is overriden. These reactionary responses are processed in a part of the brain that codes emotions, called the:”,”desc”:”The amygdala is the brain\u2019s seat of emotion, otherwise known as the alarm...

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How the brain hears and fears

Jennifer Michalowski — Wed, 05 Dec 2018 10:00:12 +0000

Cold Spring Harbor, NY — How is it that a sound can send a chill down your spine? By observing individual brain cells of mice, scientists at ��ϳԹ��Դ (CSHL) are understanding how a sound can incite fear. Investigator Bo Li focuses on a part of the mouse brain called the amygdala where...

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Scientists show how brain circuit generates anxiety

Communications Department — Tue, 29 May 2018 16:00:54 +0000

Research suggests a possible target for future anti-anxiety drugs Cold Spring Harbor, NY — Neuroscientists at ��ϳԹ��Դ (CSHL) have identified a neural circuit in the amygdala, the brain’s seat of emotion processing, that gives rise to anxiety. Their insight has revealed the critical role of a molecule called dynorphin, which could serve...

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A Halloween treat: The neuroscience of fear

Public Affairs Administrator — Tue, 31 Oct 2017 18:09:42 +0000

Halloween: It’s that time of the year when getting scared is festive! But how does fear work? New results from CSHL neuroscientists revises our knowledge of how the brain learns to fear.

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A new brain circuit that controls fear is identified

Communications Department — Mon, 19 Jan 2015 11:00:13 +0000

Researchers discover a pathway in that mouse brain that regulates fear memory and behavior Cold Spring Harbor, NY — Some people have no fear, like that 17-year-old kid who drives like a maniac. But for the nearly 40 million adults who suffer from anxiety disorders, an overabundance of fear rules their lives. Debilitating anxiety prevents...

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Dealing with stress—to cope or to quit?

Communications Department — Tue, 27 May 2014 22:10:00 +0000

Researchers identify neurons that determine whether an individual will be depressed or resilient Cold Spring Harbor, NY — We all deal with stress differently. For many of us, stress is a great motivator, spurring a renewed sense of vigor to solve life’s problems. But for others, stress triggers depression. We become overwhelmed, paralyzed by hopelessness...

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Neurobiologists find chronic stress in early life causes anxiety, aggression in adulthood

Peter Tarr — Thu, 27 Mar 2014 01:00:51 +0000

Cold Spring Harbor, NY — In recent years, behavioral neuroscientists have debated the meaning and significance of a plethora of independently conducted experiments seeking to establish the impact of chronic, early-life stress upon behavior—both at the time that stress is experienced, and upon the same individuals later in life, during adulthood. These experiments, typically conducted...

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Team demonstrates power of precision medicine in successful treatment of patient with disabling OCD

Peter Tarr — Thu, 03 Oct 2013 08:00:50 +0000

Cold Spring Harbor, NY — A multidisciplinary team led by a geneticist and psychiatrist from ��ϳԹ��Դ’s (CSHL) Stanley Institute for Cognitive Genomics today publish a paper providing a glimpse of both the tremendous power and the current limitations of what is sometimes called “precision medicine.” Precision medicine is an approach to diagnosis...

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CSHL neuroscientists pinpoint location of fear memory in amygdala

Communications Department — Sun, 27 Jan 2013 00:00:07 +0000

Fear responses based on experience are encoded in a circuit in the central amygdala Cold Spring Harbor, NY — A rustle of undergrowth in the outback: it’s a sound that might make an animal or person stop sharply and be still, in the anticipation of a predator. That “freezing” is part of the fear response,...

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