Peter Tarr, Author at ��ϳԹ��Դ

How a sleeping cancer awakens and metastasizes

Peter Tarr — Thu, 27 Sep 2018 18:00:29 +0000

Cold Spring Harbor, NY — Scientists at ��ϳԹ��Դ (CSHL) have determined one of the ways in which cancers in remission can spring back into action. This knowledge has inspired a new treatment idea designed to prevent cancer recurrence and metastasis. Even after successful cancer treatment, dormant, non-dividing cancer cells that previously detached...

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The miracle of brain development

Peter Tarr — Thu, 16 Aug 2018 15:16:33 +0000

Genetic “fate-mapping” technologies developed by (��ϳԹ��Դ) Professor Josh Huang and colleagues show in exquisite detail how an important part of the mammalian brain—here, a mouse brain—self-assembles over a few short weeks during the embryonic period. In the sequence featured below, follow the emergence of the striatum, a brain area that enables information...

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One experiment: Building a brain

Peter Tarr — Thu, 16 Aug 2018 15:14:21 +0000

We think of ourselves as unique individuals, yet developmental biology reveals what all of us must have in common before our experiences even begin to differentiate us. ��ϳԹ��Դ Professor Josh Huang and his team show in these images how a program that has evolved over eons and is imprinted in genes unfurls...

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Massive genome havoc in breast cancer is revealed

Peter Tarr — Fri, 13 Jul 2018 01:20:22 +0000

Cold Spring Harbor, NY — In cancer cells, genetic errors wreak havoc. Misspelled genes, as well as structural variations—larger-scale rearrangements of DNA that can encompass large chunks of chromosomes—disturb carefully balanced mechanisms that have evolved to regulate cell growth. Genes that are normally silent are massively activated and mutant proteins are formed. These and other...

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Progress toward improved Wilson’s disease drug

Peter Tarr — Wed, 27 Jun 2018 14:53:10 +0000

Cold Spring Harbor, NY — Researchers at ��ϳԹ��Դ (CSHL), working in collaboration with DepYmed Inc., a CSHL spinout company, today report that they have conducted promising preclinical experiments on a compound that could be used to treat Wilson’s disease and possibly other disorders—including certain types of cancer—in which levels of copper in...

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A better way to trace neuronal pathways

Peter Tarr — Wed, 06 Jun 2018 15:00:19 +0000

Moving forward by moving backward more effectively Cold Spring Harbor, NY — New technologies have been likened, famously, to magic. At first, even the few who understand how they work have a tendency to sit back and marvel. Soon, flaws and limitations are detected and the invention process begins again, resulting, almost always, in improvements....

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How pancreatic cancer spreads after surgery

Peter Tarr — Thu, 17 May 2018 18:00:44 +0000

Cold Spring Harbor, NY — Scientists at ��ϳԹ��Դ (CSHL) have solved a mystery about how pancreatic cancer spreads following surgery in patients whose tumor is successfully removed. After surgery, patients typically experience a two-week period during which their immune system is depleted as a result of a surge in post-operative stress hormone...

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Bringing immune cells back into the cancer fight

Peter Tarr — Fri, 04 May 2018 17:51:21 +0000

The human immune system protects us so reliably against most bacterial infections and viruses. We owe our lives to it. So why doesn’t it just as reliably prevent us from getting cancer? Most experts agree that the immune system does indeed suppress the formation of cancers. Immune cells vanquish viruses that by some estimates cause...

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Portrait of a Neuroscience Powerhouse

Peter Tarr — Fri, 27 Apr 2018 16:07:30 +0000

At noon every Tuesday from September through June, scenes from a revolution in neuroscience are playing out at ��ϳԹ��Դ. Week after week, over 100 scientists cram themselves into a ground-floor meeting room in the Beckman Laboratory. It’s standing-room only as everyone in the Neuroscience Program settles in to hear details of the...

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Unique communication strategy discovered in pathway controlling plant growth

Peter Tarr — Thu, 22 Mar 2018 17:10:32 +0000

Cold Spring Harbor, NY — A team of plant geneticists at ��ϳԹ��Դ (CSHL) has identified a protein receptor on stem cells involved in plant development that can issue different instructions about how to grow depending on what peptide (protein fragment) activates it. This is the first such multi-functional receptor found to work...

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One experiment: When cancer is hiding in plain sight

Peter Tarr — Thu, 01 Mar 2018 15:28:20 +0000

Everyone knows how important the immune system is—our lives utterly depend upon it. Its role in fighting bacteria and common viruses is something we take for granted. Few people know that its protection extends to viruses that can cause cancer. And yet cancer is so common. When it strikes, is the immune system letting us...

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Autism genetics study calls attention to impaired motor skills, general cognitive impairment

Peter Tarr — Wed, 07 Feb 2018 19:14:06 +0000

Cold Spring Harbor, NY — A new study of the genetic factors involved in the causation of autism spectrum disorders (ASD) draws fresh attention to the impact these illnesses have on motor skills, and more broadly on cognitive function. “Diminished motor skills appear to be an almost universal property of children with autism,” says Professor...

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Evolving sets of gene regulators explain some of our differences from other primates

Peter Tarr — Mon, 29 Jan 2018 16:00:41 +0000

Cold Spring Harbor, NY — Today, biologists add an important discovery to a growing body of data explaining why we’re different from chimps and other primate relatives, despite the remarkable similarity of our genes. The new evidence has to do with the way genes are regulated. It’s the result of a comprehensive genome-wide computational analysis...

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New method can more precisely determine when a cell has ‘cashed’ RNA ‘checks’ written by active genes

Peter Tarr — Fri, 26 Jan 2018 21:15:47 +0000

Cold Spring Harbor, NY — DNA has often been called “the book of life,” but this popular phrase makes some biologists squirm a bit. True, DNA bears our genes, which spell out the instructions our cells use to make proteins—those workhorse molecules that make just about everything in life possible. But the precise relationship between...

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CSHL’s Rob Martienssen honored with prestigious Barbara McClintock Prize

Peter Tarr — Fri, 19 Jan 2018 20:46:03 +0000

Cold Spring Harbor, NY — Rob Martienssen, Professor, HHMI Investigator, and Head of Genomics and Plant Genetics at ��ϳԹ��Դ (CSHL) has received the 2018 Barbara McClintock Prize for Plant Genetics and Genome Studies. The award and medal will be conferred during a ceremony in Saint-Malo, France, on March 24th, as part of...

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Counting chromosomes: Plant scientists solve a century-old mystery about reproduction

Peter Tarr — Thu, 18 Jan 2018 18:55:16 +0000

Cold Spring Harbor, NY — Counting is vital in nature. Counting chromosomes is something that most animals, plants and even single-celled organisms need to know how to do to assure viability and to reproduce. Today, a team of geneticists reveals a remarkable mechanism that enables plants to count their chromosomes, solving a century-old mystery. Being...

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Molecular decoy helps researchers halt and reverse acute leukemia in mice

Peter Tarr — Mon, 08 Jan 2018 17:00:55 +0000

Cold Spring Harbor, NY — Cancer researchers today announced they have developed a way of sidelining one of the most dangerous “bad actors” in leukemia. Their approach depends on throwing a molecular wrench into the gears of an important machine that sets genes into motion, enabling cancer cells to proliferate. In tests in mice, the...

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CSHL’s Bo Li receives BRAIN Initiative funding

Peter Tarr — Thu, 28 Dec 2017 14:08:48 +0000

CSHL Professor Bo Li and two collaborators at Oregon Health & Science University (OHSU) have been awarded a new grant under the BRAIN Initiative of the National Institutes of Health. The award of $5 million, apportioned over five years, supports research to better understand how paired structures called amygdalae, set deep in the brain, are...

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New method to determine before surgery which prostate tumors pose a lethal threat

Peter Tarr — Fri, 01 Dec 2017 16:38:11 +0000

Prostate cancer is common and largely nonlethal. But for some 21,000 men—a small percentage of the total, but a nonetheless substantial number—the disease is fatal. For earlier and more accurate detection, the Krasnitz and Wigler labs have devised a new method to analyze tumor biopsies to identify the most lethal forms of prostate cancer.

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Research profile: Leemor Joshua-Tor

Peter Tarr — Mon, 27 Nov 2017 18:24:48 +0000

When she was in the 7th grade, Leemor Joshua-Tor came upon a fragrant box that once held her mother’s perfume. It proved the perfect container for a set of flashcards that she was using to learn properties of the chemical elements. “I think my brain connected doing chemistry to good feelings, good smells,” she muses...

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Peter Tarr, Author at ���ϳԹ���Դ