Margaret Osborne, Author at ��ϳԹ��Դ

A new theory of brain development

Margaret Osborne — Mon, 02 Mar 2026 16:00:18 +0000

Your brain begins as a single cell. When all is said and done, it will house an incredibly complex and powerful network of some 170 billion cells. How does it organize itself along the way? ��ϳԹ��Դ neuroscientists have come up with a surprisingly simple answer that could have far-reaching implications for biology...

The post A new theory of brain development appeared first on ��ϳԹ��Դ.

Let’s get on pancreatic cancer’s nerves

Margaret Osborne — Mon, 09 Feb 2026 13:54:57 +0000

Pancreatic cancer has a lot of nerve. Notoriously tricky to detect, the disease also often resists traditional therapy. So, researchers are urgently looking for new ways to disrupt tumor formation. Though scientists know that the nervous system can help cancer spread, its role in the disease’s earliest stages remains unclear. “One phenomenon that is known...

The post Let’s get on pancreatic cancer’s nerves appeared first on ��ϳԹ��Դ.

CRISPR primes goldenberry for fruit bowl fame

Margaret Osborne — Fri, 12 Dec 2025 12:30:59 +0000

Since the dawn of agriculture around 10,000 years ago, our ancestors have saved seeds from the tastiest, largest, and most resilient crops to plant in the following season. Today, most fruits and vegetables we buy are the result of hundreds to thousands of years of selective breeding. Now, ��ϳԹ��Դ (CSHL) plant biologists...

The post CRISPR primes goldenberry for fruit bowl fame appeared first on ��ϳԹ��Դ.

Gut health à la CAR T

Margaret Osborne — Thu, 11 Dec 2025 12:30:53 +0000

Ever notice that as you get older, some foods no longer sit with you the same? This could be due to a breakdown of the intestinal epithelium, a single layer of cells that forms the organ’s lining. The intestine plays a crucial role in many health functions, including digestion. Under normal conditions, the entire intestinal...

The post Gut health à la CAR T appeared first on ��ϳԹ��Դ.

AI offers ‘roadmap’ to plant genetics

Margaret Osborne — Mon, 08 Dec 2025 12:30:47 +0000

As global temperatures rise, ��ϳԹ��Դ (CSHL) scientists work to grow stronger, more resilient crops. Yet, this process is challenging. Plants often have several related genes that control desirable traits, such as size or drought resistance. Finding genes with overlapping functions, or “redundant genes,” is a near-impossible scavenger hunt. “Most of the time,...

The post AI offers ‘roadmap’ to plant genetics appeared first on ��ϳԹ��Դ.

Her science could help you live healthier, longer

Margaret Osborne — Mon, 17 Nov 2025 12:30:51 +0000

When Corina Amor Vegas was just 7 years old, her mother, Esperanza, was diagnosed with breast cancer. Esperanza’s treatment would take over a decade. However, after participating in a clinical trial for a new cancer drug, she entered remission. Today, Amor Vegas is happy to say her mother is doing “very well.” The clinical trial...

The post Her science could help you live healthier, longer appeared first on ��ϳԹ��Դ.

Breast cancer discovery could help prevent recurrence

Margaret Osborne — Mon, 20 Oct 2025 11:30:07 +0000

Know someone who’s been diagnosed with breast cancer? There’s a good chance that person has received hormone therapy. Estrogen receptor-positive (ER+) breast cancers account for about 75 percent of cases. Hormone therapy is one of the most common and effective treatments. However, it’s far from a cure. Some ER+ tumors develop resistance. Many patients enter...

The post Breast cancer discovery could help prevent recurrence appeared first on ��ϳԹ��Դ.

The journey: One lab’s long winding road to cancer discovery

Margaret Osborne — Wed, 15 Oct 2025 11:30:59 +0000

As many as one in eight men in America will be diagnosed with prostate cancer at some point in their lives. About one in 44 will die from it. “Prostate cancer is very common,” ��ϳԹ��Դ (CSHL) Professor Lloyd Trotman says. “The vast majority of prostate cancers remain slow-growing and will never be...

The post The journey: One lab’s long winding road to cancer discovery appeared first on ��ϳԹ��Դ.

The magnetic math of breast health

Margaret Osborne — Thu, 02 Oct 2025 11:30:32 +0000

Branching isn’t just for trees. This biological process occurs in animal development, enabling organs to perform complex functions. Branch-like structures form in lungs, kidneys, and breasts, among other places. Importantly, only in female mammary glands does most branching occur years after birth. It happens during puberty and again during pregnancy as milk ducts branch out...

The post The magnetic math of breast health appeared first on ��ϳԹ��Դ.

You’ve never seen corn like this before

Margaret Osborne — Mon, 15 Sep 2025 11:30:56 +0000

Plant stem cells are crucial for the world’s food supply, animal feed, and fuel production. They lay the foundation for how plants grow. Yet, much about these mysterious building blocks remains unknown. Previous analyses have failed to locate many of the important genes that regulate how these cells function. Now, for the first time, Cold...

The post You’ve never seen corn like this before appeared first on ��ϳԹ��Դ.

NCI grants support ‘natural’ cancer research

Margaret Osborne — Mon, 11 Aug 2025 11:30:42 +0000

Complex chemical and biological processes are fundamental for all life on Earth and all the organs inside us. When something goes wrong with these processes, diseases like cancer can arise. At the ��ϳԹ��Դ (CSHL) Cancer Center, Professor John Moses and colleagues use click chemistry, a fast and reliable technique for linking molecules,...

The post NCI grants support ‘natural’ cancer research appeared first on ��ϳԹ��Դ.

A new “link” to triple-negative breast cancer

Margaret Osborne — Mon, 30 Jun 2025 14:00:38 +0000

LINC01235 is seen in red." data-description="" />Breast cancer is one of the most common cancers among women in the United States. Thanks to decades of fundamental research, it’s also one of the most curable. The exception is a particularly aggressive variant known as triple-negative breast cancer (TNBC). It accounts for 10 to 15 percent of all breast cancer cases. It disproportionately...

The post A new “link” to triple-negative breast cancer appeared first on ��ϳԹ��Դ.

The greatest challenge in the universe

Margaret Osborne — Mon, 17 Mar 2025 11:30:41 +0000

Is perception really reality? Philosophical considerations aside, scientists agree that perception certainly dictates reality. Throughout our lifetime, our brains build up a world based on what our senses detect. Often, these senses process environmental stimuli without us even realizing it. For example, the subconscious brain can pick up the rhythm of conversations or notice behavioral...

The post The greatest challenge in the universe appeared first on ��ϳԹ��Դ.

CSHL and global collaborators map Solanum pan-genome

Margaret Osborne — Wed, 05 Mar 2025 16:00:00 +0000

AI generated voice with Zachary Lippman’s actual voice About 75 percent of the world’s food comes from 12 plants. Scientists estimate up to 30,000 species are edible. Not only does this bottleneck jeopardize our food supply if a major crop is impacted by drought or disease—it also limits our choices at the grocery store. For...

The post CSHL and global collaborators map Solanum pan-genome appeared first on ��ϳԹ��Դ.

CRISPR manipulates plants’ flower powers

Margaret Osborne — Wed, 19 Feb 2025 17:00:49 +0000

AI generated voice with Zachary Lippman’s actual voice Humans have appreciated the beauty of flowers for centuries. Yet, flowers aren’t just aesthetically pleasing. They also play a crucial role in plant reproduction. In all plants, a well-studied gene with a curious name, Unusual Floral Organs (UFO), orchestrates the flowering process. UFO expression hinges on another...

The post CRISPR manipulates plants’ flower powers appeared first on ��ϳԹ��Դ.

Where are they now?

Margaret Osborne — Mon, 09 Dec 2024 12:30:47 +0000

Research is itself an educational activity. With the laws of science and nature for teachers, researchers conduct experiments to learn how life and the world work. ��ϳԹ��Դ (CSHL) is world-renowned for breakthrough bioscience research. What many outside the scientific community might not realize is that the Laboratory was founded as an educational...

The post Where are they now? appeared first on ��ϳԹ��Դ.

NeuroAI with an eye on equity

Margaret Osborne — Mon, 30 Sep 2024 11:30:28 +0000

When OpenAI released ChatGPT in November 2022, artificial intelligence quickly hit the mainstream and became a global cultural phenomenon. The chatbot dominated headlines as it authored news articles, passed the bar exam, drafted lesson plans for teachers, and even wrote code. ChatGPT became the fastest-growing consumer application ever. In the months following its launch, companies...

The post NeuroAI with an eye on equity appeared first on ��ϳԹ��Դ.

Corn’s ‘missing link’

Margaret Osborne — Wed, 07 Aug 2024 15:00:25 +0000

Teosinte Pollen Drive (TPD) is a selfish genetic system in maize-teosinte hybrids, which allows only pollen with both toxin and antidote to survive. Here, we see the pollen-producing part of the maize-teosinte hybrid. Image: Jon Cahn/Martienssen lab" data-description="" />��ϳԹ��Դ (CSHL) has begun to unravel a mystery millennia in the making. Our story begins 9,000 years ago. It was then that maize was first domesticated in the Mexican lowlands. Some 5,000 years later, the crop crossed with a species from the Mexican highlands called teosinte mexicana. This resulted in cold adaptability....

The post Corn’s ‘missing link’ appeared first on ��ϳԹ��Դ.

Every rose has its thorns … or does it?

Margaret Osborne — Thu, 01 Aug 2024 18:00:23 +0000

According to Greek mythology, red roses first appeared when Aphrodite pricked her foot on a thorn, spilling blood on a white rose. Since then, roses’ thorns have captured the imaginations of countless poets and forlorn lovers. But they aren’t the only plants with these dangerous protrusions, technically called prickles. Prickles have evolved independently in species...

The post Every rose has its thorns … or does it? appeared first on ��ϳԹ��Դ.

Pancreatic cancer’s cellular amnesia

Margaret Osborne — Mon, 17 Jun 2024 09:00:13 +0000

Things aren’t always as they seem. Take pancreatic cancer, for example. In up to one in 10 cases, researchers have documented a peculiar characteristic. Some of the pancreatic cells appear to have lost their identity. It’s as if they forget what they are. Former ��ϳԹ��Դ (CSHL) postdoc Diogo Maia-Silva, now at Massachusetts...

The post Pancreatic cancer’s cellular amnesia appeared first on ��ϳԹ��Դ.

Margaret Osborne, Author at ���ϳԹ���Դ